Results 51 to 60 of about 18,814 (259)

Modular Access to α‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

open access: yesAngewandte Chemie, EarlyView.
A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh   +4 more
wiley   +2 more sources

Imidazole as a parent π-conjugated backbone in charge-transfer chromophores

open access: yesBeilstein Journal of Organic Chemistry, 2012
Research activities in the field of imidazole-derived push–pull systems featuring intramolecular charge transfer (ICT) are reviewed. Design, synthetic pathways, linear and nonlinear optical properties, electrochemistry, structure–property relationships ...
Jiří Kulhánek, Filip Bureš
doaj   +1 more source

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

open access: yesAdvanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong   +11 more
wiley   +1 more source

Spectral Properties of Benzimidazoles [PDF]

open access: yes, 2010
Spectral Properties of Benzimidazoles Marie Lukešová Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biophysics and Physical Chemistry Abstract: This diploma thesis deals with the spectral properties of benzimidazoles ...
Lukešová, Marie
core  

In vitro anti-Leishmania activity of triclabendazole and its synergic effect with amphotericin B

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionLeishmaniasis is a neglected tropical disease, with approximately 1 million new cases and 30,000 deaths reported every year worldwide. Given the lack of adequate medication for treating leishmaniasis, drug repositioning is essential to save ...
Beatriz Santana Borges   +5 more
doaj   +1 more source

Solvent‐Free Synthesis of Ultrabright Carbon Dots With Near‐Unity Quantum Yield for High‐Performance Light‐Emitting Diodes

open access: yesAdvanced Science, EarlyView.
A rational, solvent‐free synthesis utilizing 2,6‐diaminonaphthalene produces ultrabright green‐emissive carbon dots. Regulated by a self‐limiting oxidative capping mechanism, excitons undergo ultrafast intra‐particle funneling from the nitrogen‐doped carbon core to emissive surface traps.
Hyeonjin Park   +8 more
wiley   +1 more source

Antimicrobial actions of benzimidazoles against oral streptococci

open access: yes, 2005
BACKGROUND/AIM: Benzimidazoles, such as lansoprazole and omeprazole, are used extensively as proton-pump inhibitors to control stomach acid secretion and also have antimicrobial actions against Helicobacter pylori.
Nguyen, P T M   +3 more
core   +1 more source

Treatment response of cystic echinococcosis to benzimidazoles: a systematic review [PDF]

open access: yes, 2009
Over the past 30 years, benzimidazoles have increasingly been used to treat cystic echinococcosis (CE). The efficacy of benzimidazoles, however, remains unclear.
Zwahlen, Marcel   +28 more
core   +2 more sources

Green Synthesis of Privileged Benzimidazole Scaffolds Using Active Deep Eutectic Solvent

open access: yesMolecules, 2019
The exploitation and use of alternative synthetic methods, in the face of classical procedures that do not conform to the ethics of green chemistry, represent an ever-present problem in the pharmaceutical industry.
Maria Luisa Di Gioia   +8 more
doaj   +1 more source

Protonation Modification of Commercial OPBI as Binders Toward High‐Performance High‐Temperature PEM Fuel Cells

open access: yesAdvanced Science, EarlyView.
Commercial OPBI binders is regulated via a facile formic‐acid protonation strategy without disrupting the polymer backbone. Protonation introduces positively charged benzimidazole sites, inducing interchain electrostatic repulsion that loosens chain packing, enlarges intermolecular spacing, and promotes uniform binder dispersion over catalyst surfaces.
Jinzhen Huang   +5 more
wiley   +1 more source

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