Results 81 to 90 of about 13,158 (230)

A single adulticide dose of albendazole induces cytochromes P4501A in mouflon (Ovis musimon) with dicrocoeliosis

Veterinární Medicína, 2007
Contact handling with wild or semi-domesticated animals requires limiting animal stress to minimum. In this respect, single administration of drug should be preferred in contact therapy of mouflon (Ovis musimon) infected by lancet fluke (Dicrocoelium ...
J. Lamka, V. Krizova, V. Cvilink, M. Savlik, J. Velik, L. Duchacek, B. Szotakova, L. Skalova   +7 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

An experimental and theoretical NMR study of NH-benzimidazoles in solution and in the solid state: proton transfer and tautomerism

Beilstein Journal of Organic Chemistry, 2014
This paper reports the 1H, 13C and 15N NMR experimental study of five benzimidazoles in solution and in the solid state (13C and 15N CPMAS NMR) as well as the theoretically calculated (GIAO/DFT) chemical shifts.
Carla I. Nieto, Pilar Cabildo, M. Ángeles García, Rosa M. Claramunt, Ibon Alkorta, José Elguero   +5 more
doaj   +1 more source

Sensitivity of Irish Pyrenopeziza brassicae populations to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides

Pest Management Science, EarlyView.
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur, Yong‐Ju Huang, Bruce DL Fitt, Steven Kildea   +3 more
wiley   +1 more source

Disease control in oilseed rape: Current insights and perspectives for next‐generation integrated pest management

Pest Management Science, EarlyView.
Winter oilseed rape in Europe suffers frequent pathogen losses. This review outlines key integrated pest management (IPM) strategies, rotation, residue and tillage management, optimized sowing, resistance, and targeted fungicides supported by forecasting.
Jon S West, Małgorzata Jędryczka, Nazanin Zamani‐Noor   +2 more
wiley   +1 more source

Resistance to thiophanate‐methyl and azoxystrobin in Colletotrichum species from Brazilian grapes

Pest Management Science, EarlyView.
First report of resistance to both quinone outside inhibitor (QoI; azoxystrobin) and methyl benzimidazole carbamate (MBC; thiophanate‐methyl) fungicides in Colletotrichum isolates associated with grapevine in Brazil. Abstract BACKGROUND Grape ripe rot (GRR) caused by Colletotrichum species can cause yield loss in vineyards in Southern and Northeast ...
Daniel Ricardo Maass Steiner, Camila Iavorski Zela, Debora Franco de Oliveira, Jhulia Gelain, Guido Schnabel, Louise Larissa May De Mio   +5 more
wiley   +1 more source

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

Smart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding, Zongying Li, Zaiwei Xiao, Siting Zhang, Zimai Liu, Xiaoguang Shao, Zhong Li, Wen Fu, Xusheng Shao   +8 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Вenzimidazole derivatives with anticonvulsant activity and their pharmacological targets

Сибирский научный медицинский журнал
Key biomolecular targets involved in regulating neuronal excitability are discussed, and recent findings on benzimidazole derivatives exhibiting anticonvulsant activity are presented.
A. D. Matveev, A. M. Shirshina, G. V. Pridvorov, O. Yu. Mukha   +3 more
doaj   +1 more source

Core/shell structured ZnO@SiO2-TTIP composite nanoparticles as an effective catalyst for the synthesis of 2-substituted benzimidazoles and benzothiazoles

Journal of Experimental Nanoscience, 2018
ZnO@SiO2-TTIP was synthesised as a novel heterogeneous catalyst and characterised by FT-IR, XRD, TEM, SEM and N2 adsorption-desorption. In this catalytic system, TTIP acts as a dopant agent for ZnO@SiO2 to decreases the recombination of photogenerated ...
Kiumars Bahrami, Zahra Karami
doaj   +1 more source