Results 91 to 100 of about 79,764 (263)
Codeine and Metabolite Concentrations in the Breastfed Neonate
Pediatric Anesthesia, EarlyView.ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley +1 more source
PM&R, EarlyView.Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager +3 more
wiley +1 more source
PM&R, EarlyView.Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source
Sleep Research, EarlyView.Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang +5 more
wiley +1 more source
Field immobilisation of adult Weddell seals using intramuscular butorphanol and midazolam
Veterinary Record, EarlyView.Abstract Background When working with free‐ranging phocid seals, methods of chemical immobilisation require ongoing refinement to reduce complications, particularly apnoea, during research procedures. Methods Adult Weddell seals (n = 20) at Cape Crozier, Antarctica, were chemically immobilised with intramuscular injection of butorphanol and midazolam ...
Rachel R. Holser +5 more
wiley +1 more source
Journal of Forensic Sciences, EarlyView.Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort +8 more
wiley +1 more source
Insights from a 6‐year hair drug analysis compendium in drug‐facilitated sexual assault cases
Journal of Forensic Sciences, EarlyView.Abstract Drug‐facilitated sexual assault (DFSA) may involve a diverse array of substances, including illicit drugs, prescription medications, and over‐the‐counter pharmaceuticals. Hair analysis has emerged as a valuable forensic tool, offering an extended window of detection spanning several months. However, interpreting drug concentrations in hair can
Amandine Fort +8 more
wiley +1 more source
What Causes Geographic Variation in Drug Prescribing? Evidence from Physician Migration
The RAND Journal of Economics, EarlyView.ABSTRACT In this article, we examine the importance of individual physicians in explaining the significant variation in prescription drug spending in Medicare Part D. By tracking prescribing behavior before and after physician relocations, we find that movers' prescribing converges toward the average of their new location.
David Beheshti, Seth Neller
wiley +1 more source
Comparative Clinical Trajectories Across Cannabis‐Related and Nonsubstance‐Related Psychoses
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Background Research indicates that first‐episode psychosis (FEP) with cannabis use disorder (CUD) carries a substantial disease burden, but more granular clinical trajectories of cannabis‐related psychoses remain unclear. This study examines the clinical trajectories of first clinically diagnosed FEP&CUD and cannabis‐induced psychosis (CIP) in
Antti Mustonen +7 more
wiley +1 more source
The Effect of Benzodiazepines on Catatonia: A Systematic Review and Meta‐Analysis
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Introduction Catatonia is a complex psychomotor syndrome associated with various psychiatric and somatic underlying disorders. Current treatment protocols include benzodiazepines and electroconvulsive therapy (ECT). Despite their widespread use, systematic evidence regarding efficacy and optimal benzodiazepine dosage remains limited.
L. Bot +14 more
wiley +1 more source