Results 71 to 80 of about 79,764 (263)

Impact of cenobamate on cortical responses to transcranial magnetic stimulation in people with drug‐resistant focal epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Cenobamate (CNB) is an effective antiseizure medication, though its mechanisms of efficacy remain incompletely understood. We assessed changes in cortical responses to transcranial magnetic stimulation (TMS) following CNB treatment.
Silvano R. Gefferie, Diego Jiménez‐Jiménez, Gerhard H. Visser, Robert M. Helling, Arn M. J. M. van den Maagdenberg, Josemir W. Sander, Simona Balestrini, Roland D. Thijs   +7 more
wiley   +1 more source

Genetic landscape of patients with atypical absence status epilepticus: A systematic review

Epilepsia Open, EarlyView.
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu, Giada Giovannini, Stefano Meletti   +2 more
wiley   +1 more source

Investigating the Pattern of Benzodiazepine Poisoning in Gorgan, 2008-2014

Journal of Clinical and Basic Research, 2018
Background and objectives: Benzodiazepine poisoning is one of the most important and common medical emergencies worldwide. The purpose of this study was to evaluate the pattern of poisoning with benzodiazepines in Gorgan, Iran.
Yaghoub Shayeste, Azam Delaram, Akram Pouyan Sadr, Jafar Jalilian, Danial Jafari   +4 more
doaj   +2 more sources

α4-containing GABAA receptors are required for antagonism of ethanol-induced motor incoordination and hypnosis by the imidazobenzodiazepine Ro15-4513

Frontiers in Pharmacology, 2011
Alcohol (ethanol) is widely consumed for its desirable effects but unfortunately has strong addiction potential. Some imidazobenzodiazepines such as Ro15-4513 are able to antagonize many ethanol-induced behaviors.
Sangeetha V. Iyer, Rodrigo eBenavides, Dev eChandra, James M Cook, Sundari eRallapalli, Harry L. June, Gregg E Homanics, Gregg E Homanics   +7 more
doaj   +1 more source

Alexithymia in Anorexia Nervosa, More State Than Trait? A Multi‐Dimensional Assessment of Emotion Processing in Patients With Anorexia Nervosa, Recovered Patients and Healthy Controls

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Alexithymia is implicated in both development and maintenance of Anorexia Nervosa (AN). It is unclear what defines alexithymia in AN. In this study, emotion processing related to alexithymia was examined. Method 40 patients with AN, 43 recovered (RC) patients and 35 matched healthy controls (HC) filled out questionnaires on eating ...
E. Wezenberg, S. K. Peters, A. A. van Elburg, S. H. W. Mares   +3 more
wiley   +1 more source

Flumazenil; a Medication Considered for Reversal of Benzodiazepine Overdose in Rapid Tranquillisation, but Could Administering It Be Hazardous for Both Patient and Doctor? A Rapid Review Required

BJPsych Open
Aims: Flumazenil is a benzodiazepine antagonist and competitively inhibits binding at the benzodiazepine receptor. In Northern Ireland (NI) mental health hospitals, and across other UK mental health hospitals, flumazenil is documented as the reversal ...
Rebecca Hutchinson
doaj   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source

Inadequate Efficacy of Remimazolam in Chinese Female Patients without Preoperative Benzodiazepine Exposure: A Report of Two Cases

Journal of Medical Sciences
Remimazolam, a gamma-aminobutyric acid subtype A receptor agonist, serves as a benzodiazepine (BZD) anesthetic in monitored anesthesia care and general anesthesia.
Min-Lun Hsieh, Meng-Fu Lai, Kuang-I Cheng, Zhi-Fu Wu   +3 more
doaj   +1 more source

A prospective naturalistic multicenter study on choice of parenteral medication in psychiatric emergency settings in Japan

Neuropsychopharmacology Reports, 2018
Aim To provide information about psychiatric emergency situations in Japan, we examined psychiatrists’ preference among parenteral medication since intramuscular (IM)‐olanzapine became available and clinical characteristics in patients given IM ...
Kotaro Hatta, Shigemasa Katayama, Fumiyoshi Morikawa, Atsushi Imai, Kiyoshi Fujita, Aiko Fujita, Takuya Ishizuka, Takayuki Abe, Yasuhiko Sudo, Kijiro Hashimoto, Chie Usui, Hiroyuki Nakamura, Yoshio Yamanouchi, Toyoaki Hirata, the JAST study group   +14 more
doaj   +1 more source

Development of a Novel 18F‐Labeled Radioligand for Imaging Translocator Protein With Positron Emission Tomography

iRADIOLOGY, EarlyView.
Translocator protein 18 kDa (TSPO) is a well‐established biomarker of neuroinflammation and is implicated in the pathophysiology of various neurodegenerative diseases. This study presents [18F]TSPO‐1118 ([18F]3) as a promising positron emission tomography (PET) radioligand for imaging TSPO with high affinity, robust brain uptake, and specificity in ...
Jian Rong, Chunyu Zhao, Xin Zhou, Jiahui Chen, Yabiao Gao, Zhendong Song, Yinlong Li, Zijing Li, Steven H. Liang   +8 more
wiley   +1 more source