Results 181 to 190 of about 138,894 (338)
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar+4 more
wiley +1 more source
Peptido-aminobenzophenones - Novel open-ring derivatives of 1,4-benzodiazepines.
Kentaro Hirai+6 more
openalex +2 more sources
The choroid plexus water density
Abstract Purpose To quantify normative ranges and circadian variability of the choroid plexus (ChP) water density in healthy adults. Methods Actigraphy assessments of circadian activity were performed for 5 days in healthy participants (n = 15; age = 28.5 ± 6.5 years) and subsequently participants underwent repeated, high spatial resolution proton ...
Abigail R. Dubois+8 more
wiley +1 more source
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid+14 more
wiley +1 more source
Interaction between phenytoin and the benzodiazepines. [PDF]
Frank Vajda+2 more
openalex +1 more source
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas+8 more
wiley +1 more source
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae+4 more
wiley +1 more source
Abstract Objective To perform a secondary review of low back pain (LBP) clinical practice guidelines (CPG) identified in a recently conducted systematic review and to synthesize and summarize low‐value recommendations as practices that may be candidates for deimplementation.
Daniel Tai+5 more
wiley +1 more source
Mode of action of modern tranquillizers from the benzodiazepine group: a clinical view [proceedings] [PDF]
H H Wieck
openalex +1 more source
Abstract Background Flight‐related neck pain constitutes a clinical entity related to the performance, occupational health, and flight safety of fighter pilots. Objective To investigate whether a multimodal physiotherapy program combining supervised motor control exercises with laser‐guided feedback and interferential current therapy with ...
Carlos Fernández‐Morales+4 more
wiley +1 more source