Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life [PDF]
, 2003 Background: Older adults are the main recipients of repeat prescriptions for benzodiazepine (BZD) hypnotics. BZDs can impair cognitive function and may not aid sleep when taken continuously for years.
Collins, R. +5 more
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ELECTROCHEMICAL CHARACTERIZATION OF NEW 1,5-BENZODIAZEPINE DERIVATIVES [PDF]
, 2014 Indexación: Web of Science; Scielo.Cyclic voltammetry was used to study the electrochemical behavior of new 1,5-benzodiazepine derivatives on a glassy carbon electrode. Well-defined oxidation peaks were observed in DMSO.
CATALÁN-CARO, SEBASTIÁN +2 more
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Epidemiologic assessment of benzodiazepine exposure among suicide deaths in Colorado, 2015–2017
BMC Public Health, 2020 Background Suicide rates have been climbing in the U.S., particularly in Rocky Mountain states such as Colorado. Benzodiazepines have been linked with suicidal ideation, but there have been few population level assessments of this link.
Tista Ghosh +6 more
doaj +1 more source
A TSPO ligand is protective in a mouse model of multiple sclerosis. [PDF]
, 2013 Local production of neurosteroids such as progesterone and allopregnanolone confers neuroprotection in central nervous system (CNS) inflammatory diseases.
Chechneva, Olga V +5 more
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Withdrawal-induced delirium associated with a benzodiazepine switch: a case report
Journal of Medical Case Reports, 2011 Introduction Introduced in the early 1960s, diazepam remains among the most frequently prescribed benzodiazepine-type sedatives and hypnotics. Patients with chronic use of short-acting benzodiazepines are frequently switched to diazepam because the ...
Bosshart Herbert
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Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]
, 2019 BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A +7 more
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Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
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TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control [PDF]
, 2014 The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane (OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits mitochondrial autophagy downstream of the PINK1-PARK2 pathway, preventing essential ...
Anholt R +22 more
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BMC Complementary and Alternative Medicine, 2017 Background Conventional approaches for benzodiazepine tapering have their limitations. Anecdotal studies have shown that acupuncture is a potential treatment for facilitating successful benzodiazepine tapering.
Wing-Fai Yeung +9 more
doaj +1 more source
BMC Pregnancy and Childbirth, 2021 Background Little is known about benzodiazepine and opioid-benzodiazepine co-dispensing patterns among pregnant women. Understanding these patterns is necessary to mitigate high-risk medication use during pregnancy.
Danya M. Qato, Aakash Bipin Gandhi
doaj +1 more source