Results 21 to 30 of about 132,663 (305)
The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis. [PDF]
, 2016 The mitochondrial translocator protein (TSPO) has been implicated in CNS diseases. Here, we sought to determine the specific role of TSPO in experimental autoimmune encephalomyelitis (EAE), the most studied animal model of multiple sclerosis (MS).
Chechneva, Olga +3 more
core +1 more source
Recent Trends in Metabolomics by NMR Spectroscopy
Angewandte Chemie, EarlyView.AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco +6 more
wiley +2 more sources
Characteristics of patients who were able to switch from benzodiazepine hypnotics to lemborexant
SAGE Open Medicine, 2021 Objectives: There is little evidence of insomnia treatment, especially exit strategies for hypnotics. We examined on the characteristics of patients who were able to switch from benzodiazepine hypnotics to lemborexant.
Hidenobu Suzuki, Hiroyuki Hibino
doaj +1 more source
Hemadsorption: A New Therapeutic Option for Selected Cases of Bromazepam Intoxication
Case Reports in Nephrology and Dialysis, 2022 Benzodiazepine ingestion is frequent in patients admitted to ICU for intoxications. Generally, a supportive approach by securing the airway, breathing, and circulation is sufficient.
Michaël Mekeirele +4 more
doaj +1 more source
Translocator protein in late stage Alzheimer\u27s disease and Dementia with Lewy bodies brains [PDF]
, 2019 OBJECTIVE: Increased translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR), in glial cells of the brain has been used as a neuroinflammation marker in the early and middle stages of neurodegenerative diseases, such
Bales, Kelly R +7 more
core +2 more sources
BMC Family Practice, 2009 Background Benzodiazepines are frequently prescribed to elderly patients' despite concerns about adverse effects leading to injurious falls. Previous studies have not investigated the extent to which patients with pre-existing risk factors for falls are ...
Sylvestre Marie-Pierre +4 more
doaj +1 more source
Benzodiazepine Use Before Conception and Risk of Ectopic Pregnancy
International Journal of Population Data Science, 2020 Introduction Ectopic pregnancy occurs in 1% to 2% of the all recognized pregnancies, yet half of women who have an ectopic pregnancy do not have any known risk factors.
Elizabeth Wall-Wieler +5 more
doaj +1 more source
Carbon dioxide test as an additional clinical measure of treatment response in panic disorder [PDF]
Arquivos de Neuro-Psiquiatria, 2002 OBJECTIVE: We aim to determine if a treatment with a dose of clonazepam - 2 mg/day, for 6 weeks, blocks spontaneous panic attacks and the ones induced by the inhalation of 35% carbon dioxide (CO2) in panic disorder (PD) patients.
Alexandre M. Valença +4 more
doaj +1 more source
Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data from the Veterans Aging Cohort Study [PDF]
, 2019 Background: Insomnia is associated with increased cardiovascular disease (CVD) risk in the general population and is highly prevalent in people with HIV. The CVD risk conferred by insomnia in the HIV population is unknown.
Bedimo, Roger J. +12 more
core +1 more source
Frontiers in Aging Neuroscience, 2021 Background: Gamma-aminobutyric acid (GABA) type A receptors are positively allosterically modulated by benzodiazepine binding, leading to a potentiated response to GABA.
Tomonori Furukawa +8 more
doaj +1 more source