Results 251 to 260 of about 155,585 (335)

Pre- and Postoperative Prescription of Opioids and Benzodiazepines in the US. [PDF]

J Am Coll Surg
Zhao AY, Parel PM, Maust DT, Sala-Rabanal M, Grucza RA, Park TW, Pennington BRT, Nunley RM, Avidan MS, Tang VL, Lenze EJ, Gu A, Xu KY.   +12 more
europepmc   +1 more source

Artificial intelligence‐driven closed‐loop devices in sudden unexpected death in epilepsy prediction and prevention: Insights from persons with epilepsy and caregivers

Epilepsia, EarlyView.
Abstract Objective The absence of strategies for predicting and preventing sudden unexpected death in epilepsy (SUDEP) is intertwined with the lack of studies measuring users' attitudes toward potential innovative interventions. The NEUROSENSE Project (http://www.neurosense‐project.eu) aims to evaluate novel SUDEP‐predictive neuroendocrine biomarkers ...
João Ferreira, Miguel França, Mariana Cardoso Regalo, Mariana Rei, Ricardo Peixoto, José Ángel Aibar, Torie Robinson, Ricardo Matias, Fabrice Duprat, Massimo Mantegazza, Onur Parlak, Philippe Ryvlin, Sándor Beniczky, Lígia Lopes, Emilio Perucca, João Claro, Carlos Conde   +16 more
wiley   +1 more source

Challenges of benzodiazepine deprescribing in elderly patients attending primary healthcare. [PDF]

Front Pharmacol
Tinoco MS, Carvalho Júnior SJE, Ramos AIC, Rodrigues LS, Pereira ML, Baldoni AO.   +5 more
europepmc   +1 more source

Clinical and genetic landscape of epilepsies with absence seizures and single‐gene etiology

Epilepsia, EarlyView.
Abstract Objective To characterize the clinical, electroencephalographic, and genetic features of epilepsies featuring absence seizures within monogenic etiology, highlighting the diagnostic, treatment and prognostic implications. Methods We conducted a retrospective, multicenter study including patients with monogenic epilepsies and ...
Simona Balestrini, Ilaria Galli, Maria Luisa Ricci, Elena Parrini, Davide Mei, Mario Mastrangelo, Francesco Pisani, Corinna Filippi, Lucio Giordano, Elisabetta Cesaroni, Carla Marini, Emanuele Cerulli Irelli, Carlo di Bonaventura, Marica Rubino, Antonietta Coppola, Jacopo Proietti, Tommaso Lo Barco, Francesca Darra, Laura Licchetta, Francesca Bisulli, Marco Perulli, Domenica Battaglia, Angela De Dominicis, Marina Trivisano, Nicola Specchio, Roberta Solazzi, Davide Caputo, Laura Canafoglia, LICE Collaborative group, Carmen Barba, Emanuele Bartolini, Pia Bernardo, Maria Paola Canevini, Gaetano Cantalupo, Susanna Casellato, Mara Cavallin, Ilaria Contaldo, Alessandro Ferretti, Maria Luigia Gambardella, Tiziana Granata, Giuliana Lentini, Anna Luchetti, Federico Melani, Pasquale Parisi, Simona Pellacani, Laura Pietrangelo, Tiziana Pisano, Ilaria Onida, Emilia Ricci, Aglaia Vignoli, Renzo Guerrini   +50 more
wiley   +1 more source

Sedative-hypnotic drug use and risk of falls and fractures in elderly patients: a cross-sectional study. [PDF]

BMC Geriatr
Imani MH, Imani AH, Saem A, Niksolat M.
europepmc   +1 more source

Characteristics, therapeutic pathway and the economic burden of patients with drug‐resistant epilepsy: A real‐world analysis following the introduction of cenobamate in Italy

Epilepsia, EarlyView.
Abstract Objectives Drug‐resistant epilepsy (DRE) remains a major clinical challenge, affecting approximately one‐third of patients with epilepsy. Cenobamate, a novel antiseizure medication (ASM) approved in Italy in 2022, has shown promise in clinical trials. However, real‐world data on its use, especially economic evaluations, remain limited.
Valentina Perrone, Chiara Veronesi, Maria Cappuccilli, Margherita Andretta, Marcello Bacca, Antonietta Barbieri, Fausto Bartolini, Alessandro Brega, Maria Rosaria Cillo, Francesco Colasuonno, Stefania Dell'Orco, Fulvio Ferrante, Stefano Grego, Antonella Lavalle, Daniela Mancini, Maurizio Pastorello, Romina Pagliaro, Cataldo Procacci, Camilla Scandolara, Patrizia Schiavone, Loredana Ubertazzo, Paola Valpondi, Adriano Vercellone, Alberto Zucchi, Maria Ciappetta, Domenico Lucatelli, Andrea Cinti Luciani, Luca Degli Esposti   +27 more
wiley   +1 more source

The Risk Factors and Mortality Among Patients With Different Combination Patterns of Opioids and Benzodiazepines: A Retrospective Study. [PDF]

Pharmacol Res Perspect
Su FY, Tsai MC, Ng YY, Wu SC.
europepmc   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun, Rachel Spera, John M. Williamson, Suchitra Joshi, Bhavya Guduru, Harini Ganabady, Jaideep Kapur   +6 more
wiley   +1 more source

Motivations underlying co-use of benzodiazepines and opioids in the UK: a qualitative study. [PDF]

Harm Reduct J
Vojt G, Family HE, Poulter H, Bailey CP, Cavallo D, Abdala Sheikh AP, Karimi S, Booth N, Da Silva P, Aitken L, Stewart S, Hickman M, Henderson G, Scott J, Kesten JM.   +14 more
europepmc   +1 more source

Clobazam versus corticosteroid for developmental and epileptic encephalopathy with spike–wave activation in sleep ((D)EE‐SWAS): Results of a multicenter observational study

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy with spike–wave activation in sleep ((D)EE‐SWAS) is associated with acquired cognitive and behavioral deficits. This international multicenter study aimed to compare cognitive and safety outcomes following initial treatment with corticosteroid and clobazam in patients not eligible for the ...
Marleen M. L. van Arnhem, Linde J. Vijn, Guido Rubboli, Marianne Søndergaard Khinchi, Petia Dimova, Emilio Perucca, Valentina De Giorgis, Liisa Metsähonkala, Georgia Ramantani, Anna Jansen, Richard Chin, Lieven Lagae, Alexis Arzimanoglou, Wim M. Otte, Frans S. S. Leijten, Heleen C. van Teeseling, Kees P. J. Braun, Floor E. Jansen, Bart van den Munckhof   +18 more
wiley   +1 more source