Results 261 to 270 of about 155,585 (335)

Lennox–Gastaut syndrome unveiled: Advancing diagnosis, therapies, and advocacy‐insights from the Genoa International Workshop

open access: yesEpilepsia, EarlyView.
Abstract Lennox–Gastaut syndrome (LGS) is one of the most severe, yet one of the most discussed, childhood‐onset developmental and epileptic encephalopathies (DEEs). Dissent among epileptologists on the definition and minimum set of electroclinical features derives from the high etiological heterogeneity within the syndrome, which could make its ...
Antonella Riva   +40 more
wiley   +1 more source

A survey on the awareness of a sleep-medication formulary in community health care and its influence on prescribing behavior. [PDF]

open access: yesJ Pharm Health Care Sci
Ishikawa A   +8 more
europepmc   +1 more source

Epilepsy treatment over time: The chess game analogy for choosing, adjusting, and adding antiseizure medications

open access: yesEpilepsia, EarlyView.
Abstract Recurrent seizures have such a negative impact upon the lives of persons with epilepsy that their prevention is a constant preoccupation of neurologists. Despite the large number of antiseizure medications (ASMs) currently available and of publications on their putative efficacy, adverse effects, and order of preference to start treatment ...
André Palmini   +2 more
wiley   +1 more source

Clinical trajectories and medication response in TBC1D24‐related epilepsies

open access: yesEpilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon   +9 more
wiley   +1 more source

Forensic toxicology of benzodiazepines: neuropharmacological effects, analytical challenges, and emerging detection strategies. [PDF]

open access: yesFront Toxicol
Irfan Thalib H   +6 more
europepmc   +1 more source

Meta‐analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite decades of development in anti‐seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important.
Giovanna L. Durante   +4 more
wiley   +1 more source

Benzodiazepines

open access: yes, 2017
David J. Kim, Srdjan S. Nedeljkovic
openaire   +1 more source

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