Results 261 to 270 of about 207,949 (383)

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi, Priya Atodaria, Edmund Appiah‐Kubi, Zainab Shah, Elpidio Marlon Garcia   +4 more
wiley   +1 more source

Dementia and Sleep Disorders: The Effects of Drug Therapy in a Systematic Review. [PDF]

Int J Mol Sci
Chavez-Mendoza LF, Vázquez-Alvarez AO, Torres-Mendoza BM, Trujillo-Rangel WA, Torres-Sánchez ED, Bracho-Valdés I, Delgado-Lara DLC.   +6 more
europepmc   +1 more source

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

Nature reviews. Drug discovery, 2011
U. Rudolph, F. Knoflach
semanticscholar   +1 more source

Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure

, 1987
Mark L. Bassett, Kevin D. Mullen, Phil Skolnick, E. Anthony Jones   +3 more
openalex   +1 more source

An exploratory analysis of 5‐alpha reductase inhibitors and risk of opioid use disorder among male Medicare beneficiaries receiving prescription opioid medications

The American Journal on Addictions, EarlyView.
Abstract Background Opioid use disorder (OUD) imposes a significant socioeconomic burden, highlighting the need for new interventions. Objective This study investigated whether exposure to 5‐alpha reductase inhibitors (5αRIs) is associated with a lower risk of developing OUD.
Abdelrahman G. Tawfik, Tyler Lister, Ainhoa Gomez‐Lumbreras, Randall T. Peterson, Marco Bortolato, Daniel C. Malone   +5 more
wiley   +1 more source

Concurrent Prescribing of Opioids and Sedative-Hypnotic Drugs for Long-Term Use in Australian General Practice: A Cross-Sectional Analysis Using MedicineInsight. [PDF]

Pharmacol Res Perspect
Williams S, Rositano J, Haeusler C, Bhat M, Omond K, Stocks N, Gonzalez-Chica D.   +6 more
europepmc   +1 more source

Managing Acute Behavioural Disturbance in Perinatal Women: A Systematic and State of the Art Review of Guidelines

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Guidelines for managing acute behavioural disturbance typically exclusively focus on care for adults in mental health and related settings, how this should be adapted to safely manage in pregnancy and the early postpartum including in settings such as maternity wards is less clear. Aims To undertake a systematic and state of the art
Megan Galbally, Brendan Jansen, Rebecca Hill, Bo Egan, Josephine Power, Ryan Hodges, Mathew Coleman   +6 more
wiley   +1 more source

Sedation and analgesia doses do not differ across demographic factors in pediatric cardiac surgery patients. [PDF]

Front Pediatr
Lawson NR, Achuff BJ, Ankola A, Guffey D, Lopez K, Afonso N.   +5 more
europepmc   +1 more source

Delirium identification, prevention and management in intensive care units in England, Wales and Northern Ireland: a survey of practice

Anaesthesia, EarlyView.
Summary Introduction Delirium is the most common sign of acute brain dysfunction and is prevalent in ICUs. This work is part of a UK National Institute of Health and Social Care Research‐funded Programme Development Grant to identify optimal approaches to prevent, identify and manage ICU delirium in the UK.
Ben Gibbison, Amelia Francis Johnson, Kathryn M. Rowan, Roxanne Parslow, Andrew J. Moore, Sarah C. Smith, James Long, Molly Potter, Maria Pufulete, on behalf of the OPTIC Study Group, Mike Grocott, Emma Hopkins, Alicia O'Cathain, Paul Moran, Claire Black, Cathrine McKenzie, Andy Gibson, Susie Robinson‐Molloy, Burak Kundakci, Andrew Booth, Katherine L. Jones   +20 more
wiley   +1 more source

Sleep medications and alcohol abuse masked sleep apnea syndrome without sleepiness for over 30 years: A case report. [PDF]

PCN Rep
Onishi N, Nishida K, Minami H, Toyoda K, Nishizawa Y, Kubo Y, Ikeda S, Kanazawa T.   +7 more
europepmc   +1 more source