Results 81 to 90 of about 207,949 (383)

Benzodiazepines and risk of all cause mortality in adults: cohort study

British medical journal, 2017
Objectives To evaluate the risk of all cause mortality associated with initiating compared with not initiating benzodiazepines in adults, and to address potential treatment barriers and confounding related to the use of a non-active comparator group ...
Elisabetta Patorno, R. Glynn, R. Levin, Moa P. Lee, K. Huybrechts   +4 more
semanticscholar   +1 more source

The problem of propranolol poisoning

British Journal of Clinical Pharmacology, EarlyView.
Aims Propranolol is licensed in the UK and elsewhere to relieve symptoms of anxiety. In overdose, propranolol poisoning can be serious, difficult to treat and potentially fatal. This paper describes cases of intentional propranolol overdose reported to the UK National Poisons Information Service in order to raise awareness of the risk of harm following
Hayley Williams, Pardeep Jagpal, Euan Sandilands, Emma Morrison, Laurence Gray, Harry Krishna Ruben Thanacoody, Elisha Beg, Sally Bradberry, Robin Ferner   +8 more
wiley   +1 more source

The Antidepressant Effect of Ketamine Is Dampened by Concomitant Benzodiazepine Medication

Frontiers in Psychiatry, 2020
The rapid antidepressant effect of ketamine has become a breakthrough in the research and treatment of depression. Although predictive and modulating factors of the response to ketamine are broadly studied, little is known about optimal concurrent ...
Veronika Andrashko, Veronika Andrashko, Tomas Novak, Tomas Novak, Martin Brunovsky, Martin Brunovsky, Monika Klirova, Monika Klirova, Peter Sos, Jiri Horacek, Jiri Horacek   +10 more
doaj   +1 more source

The synergistic effect of anticholinergic burden and depression on fall risk in older persons

British Journal of Clinical Pharmacology, EarlyView.
Aims Both anticholinergic burden (ACB) and depression are known to increase fall risk in older persons, next to increasing morbidity and mortality. However, the effect of depression on fall risk associated with ACB is unclear. This is relevant because several antidepressants have anticholinergic effects to some extent.
Raymond Salet, Nathalie van der Velde, Didi Rhebergen, Bob van de Loo, Lotta Seppala, Natasja M. van Schoor, Bruno Stricker, Marieke Henstra   +7 more
wiley   +1 more source

The effect of triazolam premedication on anxiety, sedation, and amnesia in general anesthesia [PDF]

Korean Journal of Anesthesiology, 2017
BackgroundBenzodiazepines have been used preoperatively as part of an anesthesia regimen to attenuate the anxiety of patients. In this study, we aimed to examine the effect of oral triazolam, a short-acting benzodiazepine, on anxiety, sedation, and ...
Taehee Pyeon, Shiyoung Chung, Injae Kim, Seongheon Lee, Seongwook Jeong   +4 more
doaj   +1 more source

Case report on antipsychotic induced catatonia in an incarcerated patient

Frontiers in Psychiatry, 2023
Antipsychotic-induced catatonia is an iatrogenic and debilitating adverse reaction, but there is a dearth of recent documented cases. This report describes a 35-year-old incarcerated Korean-American male with a history of unspecified psychosis who ...
Han Nguyen, Ruslana Cannell, Suman Rollakanti, Johanna Rosenthal, Johanna Rosenthal, David Seigler, David Seigler   +6 more
doaj   +1 more source

Emerging pharmacotherapy of tinnitus [PDF]

, 2009
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen, Azevedo AA, Bahmad FM, Berthold Langguth, Busto U, Courtney KR, Domeisen H, Feder R, Gananca MM, Goebel G, Goodnick PJ, Gresser U, Guitton MJ, Guitton MJ, Hastak SM, Henry JA, Hilton M, Holstein N, House JW, Kuchar DL, Langguth B, Lenarz T, Mahadevan S, Mardini MK, McCabe BF, Melcher JR, Moller AR, Moller AR, Newman CW, Oliver D, Podoshin L, Richard Salvi, Rogawski MA, Roth SH, Schlee W, Shambaugh GE, Shea JJ, Shulman A, Sieghart W, Tandon R, Wei BPC, Williams SH, Willow M, Zapp JJ   +43 more
core   +1 more source

What Epigenetics Teaches Us About Neuron–Glioma Interactions

BioEssays, EarlyView.
Neuron–glioma interactions through the epigenetic lens. Rewiring of epigenetic mechanisms, including alterations in the enhancer landscape and 3D chromatin organization, allows glioma cells to sense and respond to neural signals. Targeting the epigenetic machinery that facilitates this neuron–glioma crosstalk provides a strategy to disrupt the neural ...
Chaitali Chakraborty, Itzel Nissen, Silvia Remeseiro   +2 more
wiley   +1 more source

Unexpected Increase in Benzodiazepine Prescriptions Related to the Introduction of an Electronic Prescribing Tool: Evidence from Multicenter Hospital Data

Diagnostics, 2019
Electronic Prescribing tools (e-prescribing) have shown several benefits in terms of prescribing process adequacy and health care quality in hospital settings.
Rosaria Del Giorno, Carmen Schneiders, Kevyn Stefanelli, Alessandro Ceschi, Sandor Gyoerik-Lora, Irene Aletto, Luca Gabutti   +6 more
doaj   +1 more source

Benzodiazepines for delirium [PDF]

Cochrane Database of Systematic Reviews, 2009
Delirium occurs in 30% of hospitalised patients and is associated with prolonged hospital stay and increased morbidity and mortality. The results of uncontrolled studies have been unclear, with some suggesting that benzodiazepines may be useful in controlling non-alcohol related delirium.To determine the effectiveness and incidence of adverse effects ...
Almudena Areosa Sastre, Edmund Lonergan, Jay S. Luxenberg   +2 more
openaire   +3 more sources