Results 41 to 50 of about 8,220 (213)
5,6-Dihydro-2H-pyran-3(4H)-on als Baustein zur Synthese pyrananellierter Heterocyclen [PDF]
, 1984 Während 5,6-Dihydro-2H-pyran-3(4H)-on (3) sich mit ortho-substituierten Phenylcarbonylverbindungen nur in Einzelfällen regioselektiv zu pyrananellierten Heterocyclen umsetzt - z. B.
Eiden, Fritz, Wanner, Klaus Th.
core +1 more source
Synthesis of New Derivatives of Benzofuran as Potential Anticancer Agents
Molecules, 2019 The results of our previous research indicated that some derivatives of benzofurans, particularly halogeno-derivatives, are selectively toxic towards human leukemia cells.
Mariola Napiórkowska +4 more
doaj +1 more source
Molecules, 2022 A new approach for the synthesis of 2-aminobenzofurans has been described via Sc(OTf)3 mediated formal cycloaddition of isocyanides with the in situ generated ortho-quinone methides (o-QMs) from o-hydroxybenzhydryl alcohol. Notably, as a class of readily
Huaxin Lin +6 more
doaj +1 more source
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands [PDF]
, 2015 Hsp90 is a molecular chaperone of pivotal importance for multiple cell pathways. ATP-regulated internal dynamics are critical for its function and current pharmacological approaches block the chaperone with ATP-competitive inhibitors.
Agard, David A. +18 more
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Benzofuran Derivatives. I. On the Effects of Substituents in Benzofuran Syntheses [PDF]
Bulletin of the Chemical Society of Japan, 1983 Abstract The Rössing’s reaction of 4-substituted 2-acylphenoxyacetic acids give a mixture of benzofurans and 2-benzofurancarboxylic acids. The relative yields of benzofurans and 2-benzofurancarboxylic acids depend on the substituents on the benzene ring of the 2-acylphenoxyacetic acids.
Tsuneo Suzuki +3 more
openaire +1 more source
Stereoselective Synthesis of 2-(2-Aminoalkyl)- and 1,3-Disubstituted Tetrahydro-1H-pyrido[4,3-b]- Benzofuran and Indole Derivatives [PDF]
, 2016 The addition of an allenyl indium intermediate to chiral N-tert-butanesulfinyl imines 7 proceeds with high levels of diastereocontrol. The resulting homopropargylic amine derivatives 10 were transformed into 2-(2-aminoalkyl)benzofuran and indole ...
Foubelo, Francisco +2 more
core +3 more sources
2,5-Dimethyl-3-phenylsulfinyl-1-benzofuran [PDF]
Acta Crystallographica Section E Structure Reports Online, 2007 The title compound, C(16)H(14)O(3)S, was prepared by the oxidation of 2,5-dimethyl-3-phenyl-sulfanyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The phenyl ring makes a dihedral angle of 76.98 (9)° with the plane of the benzofuran fragment. The crystal structure is stabilized by π-π inter-actions between furan and benzene rings of neighbouring mol ...
Uk Lee +3 more
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Nature Communications, 2020 Enriching the chemical space of polycyclic heterocycles is of high value in chemical biology. Here, the authors report an electrooxidative protocol for the regioselective dearomative annulation of indoles and benzofurans under undivided cell conditions ...
Kun Liu +9 more
doaj +1 more source
Benzothiazole durch C-C-Spaltung von alpha-[(2-Nitrophenyl)thio]ketonen [PDF]
, 1984 Einwirkung von Ammoniak bzw. Natronlauge auf die -[(2-Nitrophenyl)thio]ketone 4, 11a-c und 16 führt unter CC-Spaltung zu den Benzothiazol-N-oxid-Derivaten 8, 12ac und 17; aus dem 3-[(2-Nitrophenyl)thio]-4-piperidon-Derivat 22 entsteht der 2 ...
Babichev +10 more
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Proceedings, 2019 Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]
Marole Maria Maluleka +1 more
doaj +1 more source