Results 11 to 20 of about 10,895 (224)
Jurnal Kedokteran Hewan, 2016 This study was purposed to inquire the activities of benzopyran (chromones) and benzofuranones (coumaranones) derivatives against Steinernema feltiae (S. feltiae). The toxicity assay against S.
Khairan Khairan +3 more
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Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators
Bioorganic & Medicinal Chemistry, 2019 We describe the synthesis of 26 compounds, small polycerasoidol analogs, that are Lipinski's rule-of-five compliant. In order to confirm key structural features to activate PPARα and/or PPARγ, we have adopted structural modifications in the following parts: (i) the benzopyran core (hydrophobic nucleus) by benzopyran-4-one, dihydrobenzopyran or ...
Bermejo, Almudena +14 more
openaire +6 more sources
Orbital: The Electronic Journal of Chemistry, 2014 Novel substituted benzopyran-2-one derivatives were synthesized by catalytic condensation reactions under reflux conditions. 4-(1,2,4-Triazolyl-3-amino)-3-nitro-2H-[1]-benzopyran-2-ones 4(a-b) were synthesized by condensation of 4-chloro-3-nitro-2H-[1 ...
Ramiz Hoti +6 more
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Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti-inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies. [PDF]
Animal Model Exp MedAdenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Moon NJ +10 more
europepmc +2 more sources
NATURAL COVALENTLY COMBINED DERIVATIVES OF 2H-1-BENZOPYRAN-2-ONE
Разработка и регистрация лекарственных средств, 2019 Coumarins, known as 2Н-1-benzopyran-2-one (or 2H-chromen-2-one), are present in remarkable amounts in plants, also have been detected in microorganisms and animal sources.
A. Z. Abyshev, C. B. Nguyen
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, 2023 Benzopyran derivatives are essential for life and are found abundantly in nature. The benzopyran compounds and their derivatives play an essential role in medicinal chemistry. The various benzopyran derivatives have been used for therapeutic effects. The
Man Vir , Singh, Ajay Kumar, Tiwari
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, 2023 Prostate, breast, and lung cancers are various human cancers that have been associated with SRC kinase mutations. Therefore, the development of potent and selective SRC kinase inhibitors is an exciting area of interest for researchers.
Pabbaraju Neeraja (17455891) +8 more
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Biomolecules, 2019 Approximately 400 Garcinia species are distributed around the world. Previous studies have reported the extracts from bark, seed, fruits, peels, leaves, and stems of Garcinia mangostana, G. xanthochymus, and G.
Ting-Hsu Chen +3 more
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Field and atom-based 3D-QSAR models of chromone (1-benzopyran-4-one) derivatives as MAO inhibitors
, 2023 Monoamine oxidases (MAOs) are flavo-enzymes that aid in the oxidative deamination of neurotransmitters like dopamine, serotonin, and epinephrine. MAO inhibitors are antidepressants that work by preventing the breakdown of brain neurotransmitters and ...
Amena Ali (10772073) +5 more
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, 2016 Stable benzannelated oxapalladacycles [−(P−P)Pd-1-C6H4-2-OCHY−] possessing chiral nonracemic bidentate phosphine ligands, (P−P) = (4S,5S)-(+)-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane ((S,S)-DIOP) or (2S,4S)-(−)-2,4-bis ...
Janelle L. Portscheller (2691865) +2 more
core +3 more sources