Photoactivatable prodrugs of butyric acid based on new coumarin fused oxazole heterocycles [PDF]
New coumarin fused oxazoles were investigated as photosensitive units for carboxylic acid groups using butyric acid as a model compound. 6-Oxo-6H-benzopyrano[6,7-d]oxazol-8-yl)methyl derivatives possessing various (hetero)aromatic substituents at ...
Ana M.S. Soares +36 more
core +1 more source
Photolytic release of bioactive carboxylic acids from fused pyran conjugates [PDF]
New ester cages bearing the coumarin (2H-benzopyran-2-one) skeleton with extended π-systems as phototriggers, for glycine and β-alanine, as models of carboxylic acid bifunctional molecules with biological relevance, were evaluated under photolysis ...
Conceição, Rafaela +3 more
core +1 more source
Antibacterial and Antifungal Properties of New Synthetic Tricyclic Flavonoids
Background/Objectives: The discovery of new molecules to which bacteria have not yet developed resistance is a significant medical priority. Synthetic flavonoids are good candidates for developing new antimicrobials.
Laura Gabriela Sarbu +2 more
doaj +1 more source
3-Hydroxy-2-(4-methylphenyl)-4H-chromen-4-one
Our work in the area of carbon-monoxide-releasing molecules led to the synthesis and crystallization of new flavone derivatives as intermediates. Herein we report the first crystal structure of the title compound, C16H12O3, a hydroxy-substituted flavone ...
Clifford W. Padgett +4 more
doaj +1 more source
Photo- and solvatochromic properties of nitrobenzospiropyran in ionic liquids containing the [NTf2]- anion [PDF]
The photo-, thermo- and solvatochromic properties of 2,3-dihydro-10,30,30-trimethyl-6-nitrospiro- [1-benzopyran-2,20-1H-indole] (BSP-NO2) were studied in ILs containing the anion [NTf2]- by UV-Vis absorption spectroscopy, ab initio molecular orbital ...
Byrne, Robert +5 more
core +1 more source
Dimethyldioxirane epoxidizes 4,5-benzoxepin to form the reactive 2,3-epoxyoxepin intermediate followed by very rapid ring-opening to an o-xylylene that immediately isomerizes to the stable product 1H-2-benzopyran-1-carboxaldehyde.
Holly M. Weaver-Guevara +3 more
doaj +1 more source
Efficient and Mild Microwave-Assisted Stepwise Functionalization of Naphthalenediimide with α-Amino Acids [PDF]
Microwave dielectric heating proved to be an efficient method for the one-pot and stepwise syntheses of symmetrical and unsymmetrical naphthalenediimide derivatives of α-amino acids.
Otto, Sijbren, +3 more
core +4 more sources
Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues [PDF]
A substantial body of evidence indicates that pharmacological activation of mitochondrial ATP-sensitive potassium channels (mKATP) in the heart is protective in conditions associated with ischemia/reperfusion injury.
Bazckó, István +8 more
core +1 more source
Potential mosquito repellent compounds of Ocimum species against 3N7H and 3Q8I of Anopheles gambiae [PDF]
Mosquitoes are exceptionally efficient in detecting their hosts for blood meal using odorant binding proteins, viz. 3N7H and 3Q8I and spread several dreadful diseases.
Allu Prasada Rao +2 more
core +1 more source
Analysis of Nebivolol hydrochloride and Valsartan in Pharmaceutical Dosage Form by High Performance Thin Layer Chromatographic Method [PDF]
A simple, accurate and precise high performance thin layer chromatographic method has been developed for the estimation of Valsartan and Nebivolol hydrochloride simultaneously from a tablet dosage form.
Alok Mukerjee +5 more
core +2 more sources

