Results 21 to 30 of about 10,895 (224)

Synthesis and Selective Coronary Vasodilatory Activity of 3,4-Dihydro-2,2-bis(methoxymethyl)-2H-1-benzopyran-3-ol Derivatives:  Novel Potassium Channel Openers

, 2016
A variety of compounds having a benzopyran such as levcromakalim generally exhibit potent antihypertensive activity. During extensive investigations aimed toward identifying K+ channel openers having selective coronary vasodilation without potent ...
Itsuo Uchida (2682556), Kengo Murakami (3018780), Shinsuke Sayama (3018783), Hidetsura Cho (2320756), Yasuyuki Kajimoto (2480266), Susumu Katoh (2682559), Hiroyuki Nakanishi (698666), Kazuo Aisaka (2682547), Hisashi Kawasaki (2210368), Hiroshi Ueno (416056)   +9 more
core   +2 more sources

Identification of Two Novel Anti-Fibrotic Benzopyran Compounds Produced by Engineered Strains Derived from Streptomyces xiamenensis M1-94P that Originated from Deep-Sea Sediments

Marine Drugs, 2013
The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties.
Lei Feng, Xue-Gong Li, Jun Xu, Tie-Sheng Han, Shu-Jie Xie, Min-Juan Xu, Ya-Hui Wang, Zhi-Gang Zhang, Zhong-Yuan You   +8 more
doaj   +1 more source

Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis

Marine Drugs, 2012
An anti-fibrotic compound produced by Streptomyces xiamenensis, found in mangrove sediments, was investigated for possible therapeutic effects against fibrosis.
Jun Xu, Song-Lin Yang, Zhi-Gang Zhang, Ping Ao, Wen-Han Lin, Dong Liu, Zhen-Hao Xu, Xiao-Meng Lang, Yi-Lei Zhao, Min-Juan Xu, Xiao-Jin Liu   +10 more
doaj   +1 more source

Structural and biological characterization of a biomolecule: (3E)-3-(2, 4, 5-trimethoxyphenyl) methylidene) - 2, 3-dihydro-4H-1-benzopyran-4-one

, 2021
The title compound, C19H18O5, has been synthesized using the Claisen-Schmidt condensation reaction from the mixture of 2,3 dihydro-4H-1-benzopyran-4-one and 2,4,5 trimethoxy benzaldehyde using ethanol as solvent.
M. Krishna Priya (11592059), K. Laavanya (11592062), G. Usha (722042), D. Angeline Shirmila (11592056), J. Hemalatha (11592050), D. Reuben Jonathan (11592053)   +5 more
core   +1 more source

Isoquinoline Alkaloids and Homoisoflavonoids from Bak and Bak

Natural Product Communications, 2008
The powdered bulbs and leaves of Drimiopsis barteri yielded two novel isoquinoline alkaloids: 5-hydroxy-7,2′,3′,4′-tetramethoxy{2H-1-}benzopyran [4,3-c]isoquinoline and 6-hydroxy-7,2′,3′,4′-tetramethoxy{2H-1-}benzopyran [4,3-c]isoquinoline, three new ...
Dieudonne Ngamga, Josephine Bipa, Pearl Lebatha, Christabel Hiza, Joan Mutanyatta, Merha-Tibeb Bezabih, Pierre Tane, Berhanu M. Abegaz   +7 more
doaj   +1 more source

Synthetic Anthocyanidins from Natural Benzopyrans [PDF]

Natural Product Communications, 2016
A hydride abstraction strategy can be used to make anthocyanidins and isoflavylium salts from benzopyrans in good yields.
Kraus, George, Geraskin, Ivan
openaire   +3 more sources

Differential effects of endothelin‐1 on the vasorelaxant properties of benzopyran and non‐benzopyran potassium channel openers [PDF]

British Journal of Pharmacology, 1992
. The effects of endothelin‐1 (ET‐1) on the vasorelaxant properties of structurally different potassium channel openers (PCOs), BRL‐38227, Ro 31–6930, SDZ PCO 400, EMD‐52692, RP‐49356 and pinacidil, were studied. . All PCOs evoked concentration‐related relaxations of ET‐1 (10 nm) or KCl (20 mm) contracted rat isolated aortic rings denuded of ...
K, Lawson, M, Barras, E, Zazzi-Sudriez, D J, Martin, J M, Armstrong, P E, Hicks   +5 more
openaire   +2 more sources

In Vivo Metabolism Study of Xiamenmycin A in Mouse Plasma by UPLC-QTOF-MS and LC-MS/MS

Marine Drugs, 2015
Xiamenmycin A is an antifibrotic leading compound with a benzopyran skeleton that is isolated from mangrove-derived Streptomyces xiamenensis.
Feng Lei, Du Gao, Xi Zhang, Jun Xu, Min-Juan Xu   +4 more
doaj   +1 more source

Antimicrobial Benzopyrans from the Receptacle of Sunflower

Bioscience, Biotechnology, and Biochemistry, 1996
The antimicrobial substances in sunflower (Helianthus annuus) were investigated. Two antifungal benzopyran derivatives, 6-acetyl-2,2-dimethyl-1,2-benzopyran (1) and 6-acetyl-7-hydroxy-2,2-dimethyl-1,2-benzopyran (2), were isolated from the ethanol extract of sunflower receptacles.
SATOH, Atsushi, UTAMURA, Hisashi, ISHIZUKA, Masato, ENDO, Natsuyo, TSUJI, Masahisa, NISHIMURA, Hiroyuki   +5 more
openaire   +2 more sources

Antibacterial and Antifungal Properties of New Synthetic Tricyclic Flavonoids

Antibiotics
Background/Objectives: The discovery of new molecules to which bacteria have not yet developed resistance is a significant medical priority. Synthetic flavonoids are good candidates for developing new antimicrobials.
Laura Gabriela Sarbu, Irina Rosca, Mihail Lucian Birsa   +2 more
doaj   +1 more source