Results 71 to 80 of about 16,959 (230)

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

ChemistryOpen, Volume 15, Issue 4, April 2026.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye, Chefikou Salami, Emilie Thiery   +2 more
wiley   +1 more source

5,6-Dihydro-2H-pyran-3(4H)-on als Baustein zur Synthese pyrananellierter Heterocyclen [PDF]

, 1984
Während 5,6-Dihydro-2H-pyran-3(4H)-on (3) sich mit ortho-substituierten Phenylcarbonylverbindungen nur in Einzelfällen regioselektiv zu pyrananellierten Heterocyclen umsetzt - z. B.
Eiden, Fritz, Wanner, Klaus Th.
core   +1 more source

Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone‐Based Derivatives

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
Chromone‐based derivatives were synthesized and evaluated for selective inhibition of tumor‐associated carbonic anhydrases IX and XII. Structure–activity relationships, docking studies, and ADMET profiling revealed promising candidates with selective tumoral isoform inhibition, supporting their potential as anticancer leads. ABSTRACT A small library of
Lisa Sequeira, Simona Distinto, Carlos Fernandes, Erica Sanna, Rita Meleddu, Marco Gaspari, Filippo Cottiglia, Alessia Onali, Andrea Angeli, Fernanda Borges, Eugenio Uriarte, Stefano Alcaro, Claudiu T. Supuran, Elias Maccioni   +13 more
wiley   +1 more source

5-Hydroxy-7-methoxy-4H-chromen-4-one

Acta Crystallographica Section E, 2008
The molecular conformation of the title compound, C10H8O4, isolated from Laretia acualis, is stabilized by a strong intramolecular hydrogen bond between the hydroxyl and carbonyl groups. The crystal packing shows π–π stacking interactions.
Iván Brito, Jorge Bórquez, Luis Alberto Loyola, Matías López-Rodríguez   +3 more
doaj   +1 more source

Synthesis and anti-norovirus activity of pyranobenzopyrone compounds [PDF]

, 2012
During the last decade, noroviruses have gained media attention as the cause of large scale outbreaks of gastroenteritis on cruise ships, dormitories, nursing homes, etc.
Chang, Kyeong-Ok, Hua, Duy H., Kim, Yunjeong, Lu, Jianyu, Nguyen, Thi D.T., Pokhrel, Laxman, Prior, Allan M.   +6 more
core   +1 more source

Propolis‐Based Hybrid Nanoflowers as Multifunctional Nanozymes: Structural Integration of Polyphenols for Enhanced Catalytic and Antioxidant Activity

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT Propolis is a polyphenol‐rich natural resin with well‐documented antioxidant activity; however, its practical application is restricted by poor aqueous solubility and limited stability. Herein, propolis‐based organic–inorganic hybrid nanoflowers (Prp‐Nfs) were synthesized by integrating a propolis extract into a Cu3(PO4)2·3H2O matrix under ...
Cevahir Altinkaynak, Fatih Kirmizikar
wiley   +1 more source

Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma : a preclinical F98 glioblastoma rat model study [PDF]

, 2019
Purpose Even with an optimal treatment protocol, the median survival of glioblastoma (GB) patients is only 12-15 months. Hence, there is need for novel effective therapies that improve survival outcomes.
Bonte, Ellen, De Meulenaere, Valerie, De Wever, Olivier, Deblaere, Karel, Descamps, Benedicte, Goethals, Ingeborg, Kalala Okito, Jean-Pierre, Leybaert, Luc, Pieters, Leen, Vanhove, Christian, Verhoeven, Jeroen, Vral, Anne   +11 more
core   +1 more source

Synthesis of Isochromans From Anacardic Acids Obtained From Cashew Nutshell Liquid (CNSL) and Their Antimicrobial Activity

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Utilizing anacardic acid derived from cashew nut shell liquid, the synthesis of isochromans was accomplished. Two key steps were exploited. Firstly, a benzylic bromination in the green solvent tert‐butyl acetate is disclosed. Secondly, as an example, the exposure of the secondary alcohol 1‐(2‐methoxy‐6‐(pentadec‐1‐en‐1‐yl)phenyl)ethanol to potassium t ...
Bianca L. Davids, Tianqi Lu, Kennedy J. Ngwira, Manuel A. Fernandes, Sandy van Vuuren, Charles B. de Koning   +5 more
wiley   +1 more source

Investigation of molecular design, synthesis, and biological assessment of new benzopyran derivatives

Journal of Applied Pharmaceutical Research
Background: Tuberculosis (TB) remains a global health challenge, necessitating the discovery of novel anti-tubercular agents. The N-(8-hydrazinyl-3,4-dihydro-2H-1-benzopyran-6-yl)-N'-phenyl urea (HSM-II) scaffold has shown potential in developing ...
Mahesh Agasa Ramu, Somashekhar Metri, Trupti A Hunnura, Koushallya Patil, Hanamant B Sannakki   +4 more
doaj   +1 more source

Chemotherapeutic Potential of 2-[Piperidinoethoxyphenyl]-3-Phenyl-2H-Benzo(b)pyran in Estrogen Receptor- Negative Breast Cancer Cells: Action via Prevention of EGFR Activation and Combined Inhibition of PI-3-K/Akt/FOXO and MEK/Erk/AP-1 Pathways.

PLoS ONE, 2013
Inhibition of epidermal growth factor receptor (EGFR) signaling is considered to be a promising treatment strategy for estrogen receptor (ER)-negative breast tumors.
Ruchi Saxena, Vishal Chandra, Murli Manohar, Kanchan Hajela, Utsab Debnath, Yenamandra S Prabhakar, Karan Singh Saini, Rituraj Konwar, Sandeep Kumar, Kaling Megu, Bal Gangadhar Roy, Anila Dwivedi   +11 more
doaj   +1 more source