Results 71 to 80 of about 10,895 (224)

A novel synthesis of thiazolyl, imidazothiadiazolyl, and thiadiazinyl-2H-1-benzopyran-2-ones

, 1986
3-Acetylcoumarins I with arylthiourea in the presence of iodine gave substituted 3-(2-arylamino-4-thiazolyl)-2H-1-benzopyran-2-ones (IIa-IIc). The structures of these products have been confirmed and they were converted into acetyl derivatives (IId-IIf).
T. V. Padmanabha Rao, V. Rajeswar Rao, M. S. Rao   +2 more
core   +1 more source

Investigation of molecular design, synthesis, and biological assessment of new benzopyran derivatives

Journal of Applied Pharmaceutical Research
Background: Tuberculosis (TB) remains a global health challenge, necessitating the discovery of novel anti-tubercular agents. The N-(8-hydrazinyl-3,4-dihydro-2H-1-benzopyran-6-yl)-N'-phenyl urea (HSM-II) scaffold has shown potential in developing ...
Mahesh Agasa Ramu, Somashekhar Metri, Trupti A Hunnura, Koushallya Patil, Hanamant B Sannakki   +4 more
doaj   +1 more source

Chemotherapeutic Potential of 2-[Piperidinoethoxyphenyl]-3-Phenyl-2H-Benzo(b)pyran in Estrogen Receptor- Negative Breast Cancer Cells: Action via Prevention of EGFR Activation and Combined Inhibition of PI-3-K/Akt/FOXO and MEK/Erk/AP-1 Pathways.

PLoS ONE, 2013
Inhibition of epidermal growth factor receptor (EGFR) signaling is considered to be a promising treatment strategy for estrogen receptor (ER)-negative breast tumors.
Ruchi Saxena, Vishal Chandra, Murli Manohar, Kanchan Hajela, Utsab Debnath, Yenamandra S Prabhakar, Karan Singh Saini, Rituraj Konwar, Sandeep Kumar, Kaling Megu, Bal Gangadhar Roy, Anila Dwivedi   +11 more
doaj   +1 more source

Synthesis of benzofurans and benzopyrans

, 2002
Syntheses of 2,3-dihydrobenzofurans and 3,4-dihydrobenzopyrans normally involve several stages, therefore efficient syntheses of these compounds are desirable. A number of 3,4-dihydrobenzopyrans derivatives were prepared in one pot syntheses. The reaction is thought to proceed through cation intermediates, involving allylic cations generated by the ...
openaire   +2 more sources

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

, 2016
This study was aimed at evaluating, on a limited number of benzopyran compounds, whether the insertion of an electron-rich spirocyclic substituent at the C4 carbon of the benzopyran molecular nucleus may improve the cardioprotective properties against ...
Filippo Minutolo (1343184), Simona Rapposelli (1577473), Maria C. Breschi (1900528), Aldo Balsamo (2403889), Vincenzo Calderone (1900531), Federica Tonelli (2409481), Lara Testai (1900537), Alma Martelli (1900519)   +7 more
core   +1 more source

Multifunctional Spirocyclic Systems

International Journal of Photoenergy, 2009
New spiropyrans with different substituents in the benzopyran fragment have been synthesized and investigated. It was shown that introduction of aldehyde group in the structure of spiropyrans gives a possibility to obtain new functionalized compounds ...
Boris Lukyanov, Gennadii Vasilyuk, Eugene Mukhanov, Leonid Ageev, Maria Lukyanova, Yury Alexeenko, Serguei Besugliy, Valeri Tkachev   +7 more
doaj   +1 more source

Synthesis and in Vitro Antioxidant Activity Evaluation of 3-Carboxycoumarin Derivatives and QSAR Study of Their DPPH• Radical Scavenging Activity

Molecules, 2012
The in vitro antioxidant activities of eight 3-carboxycoumarin derivatives were assayed by the quantitative 1,1-diphenyl-2-picrylhydrazil (DPPH•) radical scavenging activity method.
Maria Teresa Sumaya-Martínez, Zeferino Gómez-Sandoval, Daniel Jaramillo Cano, Manuel Villanueva-García, Francisco J. Martínez-Martínez, Rodrigo Said Razo-Hernández, Ana Lilia Peraza-Campos   +6 more
doaj   +1 more source

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

, 2006
This study was aimed at evaluating, on a limited number of benzopyran compounds, whether the insertion of an electron-rich spirocyclic substituent at the C4 carbon of the benzopyran molecular nucleus may improve the cardioprotective properties against ...
BRESCHI, MARIA CRISTINA, MARTELLI, ALMA, BALSAMO, ALDO, TESTAI, LARA, TONELLI F, MINUTOLO, FILIPPO, CALDERONE, VINCENZO, RAPPOSELLI, SIMONA   +7 more
core   +1 more source

Characterization of the xiamenmycin biosynthesis gene cluster in Streptomyces xiamenensis 318.

PLoS ONE, 2014
Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to ...
Yong Yang, Ling Fu, Jinlong Zhang, Linghan Hu, Minjuan Xu, Jun Xu   +5 more
doaj   +1 more source