Results 81 to 90 of about 10,895 (224)
, 2005 Over the years, it has been shown that natural products that act as highly specific modulators of protein function are complex in nature, highly functionalized and contain few stereogenic centers.
Cumaranatunga-Ilangasinghe, P. Kamani
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Computer programs for calculating pKa: a comparative study for 3-(3-(2-nitrophenyl)prop-2-enoyl)-2H-1-benzopyran-2-one [PDF]
Journal of the Serbian Chemical Society, 2010 Coumarin-based compounds containing a chalcone moiety exhibit antimicrobial activity. These substances are potential drugs and it is important to determine their pKa values. However, they are almost insoluble in water.
SELMA ŠPIRTOVIĆ-HALILOVIĆ +1 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 While progress has been made in treating cancer, cytotoxic chemotherapeutic agents are still the most widely used drugs and are associated with severe side-effects.
Jalisa H. Ferguson +6 more
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5′,6-Dichloro-1′,3′,3′-trimethylspiro[2H-1-benzopyran-2,2′-indoline]
Acta Crystallographica Section E, 2008 In the crystal structure of the title compound, C19H17Cl2NO, the indoline and benzopyran ring systems are approximately perpendicular to each other. The indoline ring is in an envelope conformation with the spiro C atom as the flap.
Nameer Alhashimy +3 more
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Rotenone: from modelling to implication in Parkinson’s disease
Folia Neuropathologica, 2019 Rotenone ([2R-(2α,6aα,12aα)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyran[3,4-b]furo [2,3-h][1]benzopyran-6(6aH)-one) is a naturally occurring compound derived from the roots and stems of Derris, Tephrosia, Lonchocarpus and ...
Khaled Radad +6 more
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8-Hydroxy-5,6,7-trimethoxy-2-phenyl-4H-chromen-4-one
Acta Crystallographica Section E, 2008 In the title compound, C18H16O6, the benzopyran group is essentially planar, with the O atoms of the substituent groups lying close to its mean plane. The molecular conformation is governed by intramolecular interactions.
J. Ellena +4 more
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, 1989 5-Hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one ( tectochrysin ) (1), 5-hydroxy-7,8-di-methoxy-2-phenyl-4H-1-benzopyran-4-one (7-0-methylwogonin) (2), 5-hydroxy-6,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one (6,7-O,O-dimethylbacaiein) (3) and 2,5 ...
AH White +4 more
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Solid-Phase Parallel Synthesis of Drug-Like Artificial 2<em>H</em>-Benzopyran Libraries
Molecules, 2012 This review covers the construction of drug-like 2<em>H</em>-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran ...
Young-Dae Gong, Taeho Lee
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A REVIEW OF BENZOPYRAN DERIVATIVES IN PHARMACOTHERAPY OF BREAST CANCER
, 2018 One of the naturally occurring compounds containing oxygen moiety is benzopyran. Depending on its substitution pattern, different biological effects are shown. The benzopyran ring system is present in many natural products (such as genistein, hesperidin,
Md. Azizur, Rahman +4 more
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Synthesis and Antimicrobial Activities of Some Sulphur Containing Chromene Derivatives
Natural Product Communications, 2012 A series of 3,3-dimethyl-3 H benzothieno[3,2- f ][1]-benzopyran analogues modified at the pyran 1,2-double bond were synthesized. The corresponding dihydro and (±)-cis-diol derivatives were converted into diacetate and cyclic carbonate upon acylation ...
Tuba Şerbetçi +4 more
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