Results 71 to 80 of about 475 (128)

[Benzothiadiazine in pregnancy toxemias].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1966
H, Jenssen, S C, Sommerfelt, E K, Brodwall   +2 more
openaire   +1 more source

Activation of extrasynaptic GABA(A) receptors inhibits cyclothiazide-induced epileptiform activity in hippocampal CA1 neurons. [PDF]

Neurosci Bull, 2014
Wan L, Liu X, Wu Z, Ren W, Kong S, Dargham RA, Cheng L, Wang Y.   +7 more
europepmc   +1 more source

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Hydrolysis of Benzothiadiazines

Journal of Pharmaceutical Sciences, 1971
The hydrolysis of hydrochlorothiazide and two other hydrothiazides was studied as a function of pH. Reversible kinetics were observed for the hydrolytic reaction, and a bell-shaped pH-rate profile was obtained. The equilibrium constant, however, was relatively independent of hydrogen-ion concentration.
J A, Mollica, C R, Rehm, J B, Smith, H K, Govan   +3 more
exaly   +3 more sources

Determination of kinetic parameters of enantiomerization of benzothiadiazines by DCXplorer

Chirality, 2010
AbstractBenzothiadiazines differently substituted at the sulfonamidic nitrogen atom, at the stereogenic carbon atom and at the anilinic nitrogen atom have been synthesized and fully characterized. Enantioseparation of these compounds has revealed rapid on‐column enantiomerization.
Daniela Braghiroli, Alessandro Troisi, Giuseppe Cannazza   +2 more
exaly   +5 more sources

Hypotensive 1,2,4-Benzothiadiazines

Journal of Medicinal Chemistry, 1963
B A, BIERBAUM, J J, TRAVERSO, C W, WHITEHEAD   +2 more
exaly   +3 more sources

Syntheses of 1,2,4-benzothiadiazine 1-oxides and 1,2,4-benzothiadiazines

Journal of Organic Chemistry, 1980
Neville Finch
exaly   +2 more sources

DIABETOGENIC ACTION OF BENZOTHIADIAZINES

Lancet, The, 1963
Russell Fraser, C T Dollery
exaly   +2 more sources

Some 1H-4,1,2-benzothiadiazines and 1H-4,1,2-benzothiadiazine 4,4-dioxides

Journal of the Chemical Society, Perkin Transactions 1, 1978
Interamolecular displacement of the o-nitro-group of 1-(2-nitrophenylthio)pyruvaldehyde 1-phenylhydrazone, under basic conditions, gives 3-acetyl-1-phenyl-1H-4,1,2-benzothiadiazine which was oxidised to the 4,4-dioxide. Ethyl 2-nitrophenylsulphonylglyoxylate phenylhydrazone gives only 2-nitrodiphenylamine under these conditions, but reduction to the 2 ...
Donald E. Ames, Sosale Chandrasekhar, Kristian J. Hansen   +2 more
openaire   +2 more sources

A Potent New Benzothiadiazine Diuretic

Nature, 1960
SINCE the discovery of chlorothiazide by Beyer et al. 1, a number of chemically related compounds have been shown to possess similar natriuretic and chloruretic actions2–4. Some of these agents, notably 3,4-dihydrochlorothiazide and its derivatives, differ from chlorothiazide primarily in a greater milligram potency, which may be associated with a ...
R M, TAYLOR, M M, WINBURY
openaire   +2 more sources

Copper-promoted aerial oxidation of benzothiadiazines: access to benzothiadiazine S-oxide heterocycles

Dalton Transactions, 2015
Aerial oxidation of benzothiadiazines selectively affords the corresponding benzothiadiazine S -oxides in the presence of Cu 2+ ions. Structural studies reveal that the S -oxide appears to be a strong hydrogen ...
Ewan R, Clark, John J, Hayward, Bryce J, Leontowicz, Muhammad U, Anwar, Melanie, Pilkington, Jeremy M, Rawson   +5 more
openaire   +2 more sources