Results 101 to 110 of about 6,902 (250)
Molecules, 2002 The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and ...
Pavel Pazdera, Walid M. Fathalla
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Scientia Pharmaceutica, 2020 In order to identify new regularities of the “structure−analgesic activity” relationship in the series of 2,1-benzothiazine derivatives, the synthesis of methyl 4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate and a group ...
Igor V. Ukrainets +6 more
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Dopaminergic neuron-specific oxidative stress caused by dopamine itself [PDF]
, 2008 Oxidative stress, including the reactive oxygen or nitrogen species generated in the enzymatical oxidationor auto-oxidation of an excess amount of dopamine, is thought to play an important role in dopaminergic neurotoxicity.
Asanuma, Masato, Miyazaki, Ikuko
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2,1-Benzothiazines : preparation and reactivity [PDF]
, 2018 Title from PDF of title page (University of Missouri--Columbia, viewed on May 24, 2010). ; The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. ; Dissertation advisor: Dr. Michael Harmata. ; Vita. ; Ph. D. University of Missouri--
openaire +2 more sources
The Plant Journal, Volume 122, Issue 2, April 2025.SUMMARY Over the past few decades, significant advancements have been made in understanding how plasma‐membrane localised receptor kinases (RKs) detect signals and activate responses to various stimuli. Numerous examples of ligand‐induced receptor activation mechanisms and their downstream consequences have been characterised in detail.
Sergio Martin‐Ramirez +2 more
wiley +1 more source
Molecular docking and simulation of Zika virus NS3 helicase
BMC Chemistry, 2019 The Zika virus (ZIKV) has gained attention for the last few years due to the congenital microcephaly and Guillain–Barre Syndrome that resulted in humans. The non-structural protein-3 (NS3) helicase of ZIKV play an important role in viral RNA replication.
Syed Lal Badshah +7 more
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Synthesis of new aminohydrazone and their physical, chemical and biological properties [PDF]
, 2013 В рамках данной работы осуществлен синтез большой серии амидразонов, аминогруппа которых является частью циклического фрагмента, и проведено исследование реакций с этилхлорформиатом, хлорангидридом циклогексанкарбоновой кислоты и оксалилхлоридом ...
Eliseeva, A. I. +1 more
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Fluorination methods in drug discovery [PDF]
, 2016 Fluorination reactions of medicinal and biologically-active compounds will be discussed. Late stage fluorination strategies of medicinal targets have recently attracted considerable attention on account of the influence that the fluorine atom can impart ...
Bonesi, Sergio Mauricio +2 more
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On the deprotonation of chlorothiazide
Acta Crystallographica Section C, Volume 81, Issue 2, Page 102-108, February 2025.The structures of the Na and K salt forms of chlorothiazide have been re‐investigated and are found to have different hydration states and deprotonation sites from those described previously. The structure of the Cs salt form is found to contain the same anion as in the new models for the Na and K salt forms.Three alkali metal salt forms of the ...
Rowan K. H. Brydson +5 more
wiley +1 more source
Synthesis, antimalarial activity, structure–activity relationship analysis of thieno-[3,2-b]benzothiazine S,S-dioxide analogs [PDF]
, 2008 An improved procedure for the synthesis of 3-amino-9-arylsubstituted-thieno[3,2-b]benzothiazine S,S-dioxide 2-decarboxylated is reported. Thieno-[3,2-b]benzothiazine S,S-dioxide derivatives were investigated for their abilities to inhibit β-hematin ...
Andujar, Sebastian Antonio +10 more
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