Results 191 to 200 of about 6,902 (250)

Rearrangement of benzothiazine sulphoxides

Journal of the Chemical Society D: Chemical Communications, 1970
The reaction of substituted benzothiazine sulphoxides with Ac2O under reflux leads by an elimination reaction to a sulphenic acid derivative which undergoes subsequent addition to the generated double bond if the nitrogen is tertiary but is trapped as a cyclic sulphenamide by a secondary nitrogen.
Robert B. Morin, Douglas O. Spry
openaire   +1 more source

Preparation of S-2-halophenyl-2,1-benzothiazines

Tetrahedron, 2021
Derivatives of 2,1-benzothiazines are useful synthetic intermediates for a variety of applications. We became interested in developing a one-pot procedure to S-2-halophenyl-2,1-benzothiazines as potential precursors to P,N type ligands for metals. Accordingly, we reacted S-2-halophenyl-S-methylsulfoximines with 2-bromobenzaldehydes using the Buchwald ...
Aswin Garimalla, Michael Harmata
openaire   +2 more sources

1,4-Benzothiazines, Dihydro-1,4-benzothiazines, and Related Compounds.

1985
Publisher Summary The benzothiazines constitute a group of heterocyclic compounds; they have found a variety of industrial uses and show promise as herbicides. This chapter discusses the chemistry of 1,4-benzothiazines and dihydro-1,4-benzothiazines. The 1,4-benzothiazine ring is the basic unit for the phaeomelanins and trichochrome melanin pigments ...
C. Brown, R.M. Davidson
openaire   +1 more source

A New, Chiral Bis-Benzothiazine Ligand

Organic Letters, 2001
[reaction: see text]. The synthesis and application of a new, chiral bis-benzothiazine ligand are described.
M, Harmata, S K, Ghosh
openaire   +2 more sources

Modular Synthesis of 1,2-Benzothiazines and 1,2-Benzothiazine 1-Imines via Palladium-Catalyzed C-H/C-C Activation Reactions.

Journal of Organic Chemistry
In this study, a modular approach toward cyclic sulfoximines and sulfondiimines via palladium-catalyzed intramolecular C-H/C-C activation reactions was reported.
Yifan Ren, Lisha Mo, Yali Wang, Limin Yu, Minhai Yin, Zhuang Xiong, Fan Teng, Yimiao He   +7 more
semanticscholar   +1 more source

New benzoxazine and benzothiazine dyes

Tetrahedron, 1976
Abstract 2H-1,4-benzoxazine can be generated in situ from 1-(o-aminophenoxy)-2,2′-dimethoxyethane in trifluoroacetic acid whence further reaction leads to the benzoxazine bye 7. The benzothiazine dye 9 can be derived in similar fashion from 1-(o-aminophenylthio)-2,2-diethoxyethane.
F. Chioccara, G. Prota, R.H. Thomson
openaire   +1 more source

Synthesis of Sulfonimidamide based 1,2‐Benzothiazine via [4+2] Oxidative Annulation of Sulfonimidamide and Alkyne in Water Under Visible Light

Annalen der Pharmacie
Herein, we disclose a visible light induced Rh‐catalyzed oxidative C–H/N–H bond activation of sulfonimidamide (SIA) and subsequent [4+2] annulation with alkyne in water to yield SIA based 1,2‐benzothiazine in good to very good yield in short time ...
K. Natarajan, S. Ravindra, V. Priya, R. Kataria, G. Nandi   +4 more
semanticscholar   +1 more source

Further Studies of Benzothiazine Metalation

Synthesis, 2013
Treatment of benzothiazines 3 and 8 with butyllithium resulted in deprotonation at C3 to afford the corresponding organolithium species. These compounds could be trapped with a variety of electrophiles to give products in high yield. Some limitations to the processes chiefly based on steric effects were uncovered.
Michael Harmata, Nathan Calkins
openaire   +1 more source

1,3-Benzothiazines (review)

Chemistry of Heterocyclic Compounds, 1979
Data on the methods for the synthesis of 1,3-benzothiazines and their derivatives and their chemical properties and physiological activity are correlated.
openaire   +1 more source

Azole derivatives of 1,4-benzothiazine as antifungal agents

Bioorganic and Medicinal Chemistry, 1998
A series of azole derivatives of 1,4-benzothiazine 7-14 was synthesized and evaluated for the in vitro and in vivo activity against Candida albicans. Secondary alcohol 10 and its ether derivative 13 showed very good efficacy against systemic candidiasis in a murine experimental model.
Lucia Pitzurra, Anna Vecchiarelli
exaly   +5 more sources