Results 21 to 30 of about 77,454 (243)

Synthesis, physical-chemical and biological properties of 7-benzyl-3-methyl-8-thioxanthine derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Introduction . Interest to the problem of creating new effective antimicrobial agents among xanthine derivatives does not decrease. Primarily, this is due to the increasing of microbial resistance to conventional antimicrobial agents and the emergence of
D. H. Ivanchenko, M. I. Romanenko, O. M. Kamyshnyi, N. M. Polishchuk, K. V. Aleksandrova   +4 more
doaj   +1 more source

Effect of side-chain length in lignin model compound on MnO2 oxidation: comparison of oxidations between C6-C2- and C6-C1-type compounds

Journal of Wood Science, 2021
Monomeric C6-C2-type lignin model compounds with a p-hydroxyphenyl (H), guaiacyl (G), syringyl (S), or p-ethylphenyl (E) nucleus (1-phenylethanol derivatives) were individually oxidized by MnO2 at a pH of 1.5 and room temperature.
Shirong Sun, Tomoya Yokoyama
doaj   +1 more source

Spectral resolving of propofol and benzyl alcohol mixture [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2023
Two simple spectrophotometric methods are proposed for the spectral resolving of propofol and benzyl alcohol in their synthetic mixture. 1st derivative spectrophotometry (Method I) is used for the determination of propofol at 324.1 nm with no significant
Hesham Ramadan, Randa Abdel Salam, mohamed salim, Ghada Hadad, Fathalla Belal   +4 more
doaj   +1 more source

Synthesis, biological evaluation, and computational studies of N-benzyl pyridinium–curcumin derivatives as potent AChE inhibitors with antioxidant activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
A library of N-benzylpyridinium-based compounds, 7a-j and 8a-j, was designed and synthesised as potential acetylcholinesterase) AChE (inhibitors. An in vitro assay for the synthesised compounds showed that most compounds had significant AChE inhibitory ...
Nafisah M. Al-Rifai, Nemeh M. Al-Khalileh, Jalal A. Zahra, Musa I. El-Barghouthi, Fouad H. Darras   +4 more
doaj   +1 more source

Synthesis and physical-chemical properties of 3-benzyl-8-propylxanthine and its water-soluble salts

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Aim. Selection of basic compounds is a key moment of the novel drug substances development process. Nowadays, it is possible to model the properties of biologically active substances with the help of computer technologies and the special software.
E. K. Mikhal’chenko, K. V. Аleksandrova , S. V. Levich   +2 more
doaj   +1 more source

Purification and Evaluation of N-benzyl Cinnamamide from Red Seaweed Gracilaria fisheri as an Inhibitor of Vibrio harveyi AI-2 Quorum Sensing

Marine Drugs, 2020
Previously, we reported that the ethanol extract from red seaweed Gracilaria fisheri effectively decreased biofilm formation of Vibrio harveyi. In this study, the anti-biofilm active compounds in the ethanol extract were isolated and their structures ...
Kulwadee Karnjana, Saksit Nobsathian, Chumporn Soowannayan, Wei Zhao, Ya-Jie Tang, Kanokpan Wongprasert   +5 more
doaj   +1 more source

Proline-Based Carbamates as Cholinesterase Inhibitors

Molecules, 2017
Series of twenty-five benzyl (2S)-2-(arylcarbamoyl)pyrrolidine-1-carboxylates was prepared and completely characterized. All the compounds were tested for their in vitro ability to inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), and
Hana Pizova, Marketa Havelkova, Pavel Bobal, Sarka Stepankova, Tereza Kauerova, Andrzej Bak, Peter Kollar, Violetta Kozik, Michal Oravec, Ales Imramovsky, Josef Jampilek   +10 more
doaj   +1 more source

Antibacterial Activity of Benzyl Benzoate and Crotepoxide from Kaempferia rotunda L. Rhizome

Indonesian Journal of Chemistry, 2019
Benzyl benzoate and crotepoxide are the major components of Kaempferia rotunda L. rhizome. However, the bioactivity study of benzyl benzoate and crotepoxide as the antibacterial activity were still limited. Therefore, the antibacterial activity of benzyl
Hartiwi Diastuti, Mochammad Chasani, Suwandri Suwandri   +2 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives

Molecules, 2004
In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 ...
A. Demirdağ, A. Cansız, M. Koparır   +2 more
doaj   +1 more source