Results 1 to 10 of about 3,222 (114)
Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure [PDF]
Scientific Reports, 2023 Xanthines such as caffeine and theobromine are among the most consumed psychoactive stimulants in the world, either as natural components of coffee, tea and chocolate, or as added ingredients.
Hong Mao +12 more
doaj +2 more sources
Chemistry, 2021 In this paper, a simple and clean process for the alkylation and arylation of nitrogen-containing heterocycles is reported. The reactions were conducted using the Q-tube® as a non-conventional technology, in water as a green solvent, at overboiling ...
Lenardão E J +2 more
exaly +3 more sources
Xanthines Studied via Femtosecond Fluorescence Spectroscopy
Molecules, 2016 Xanthines represent a wide class of compounds closely related to the DNA bases adenine and guanine. Ubiquitous in the human body, they are capable of replacing natural bases in double helices and give rise to four-stranded structures. Although the use of
Thomas Gustavsson +2 more
exaly +3 more sources
Recent Advances in the Synthesis of Xanthines: A Short Review [PDF]
Scientifica, 2022 Xanthine and its derivatives are considered a pharmacologically potential moiety that manifests immense biological activities. Owing to this much diversity in the biological field, this scaffold has fascinated the attention of many researchers around the
Anandi Kapri, Nitin Gupta, Sumitra Nain
doaj +2 more sources
Green Processing and Synthesis, 2021 A green, simple one-pot microwave-assisted synthesis of xanthines and pyrimidopetridines was developed with a high EcoScale and yields.
Sara M Mostafa +2 more
exaly +2 more sources
Diagnosing Parkinson’s disease and monitoring its progression: Biomarkers from combined GC-TOF MS and LC-MS/MS untargeted metabolomics [PDF]
HeliyonParkinson's disease (PD) is a prevalent neurodegenerative disorder with a poorly understood etiology. An accurate diagnosis of idiopathic PD remains challenging as misdiagnosis is common in routine clinical practice.
Lina A. Dahabiyeh +4 more
doaj +2 more sources
Molecules, 2021 Antimicrobial resistance is a major healthcare threat globally. Xanthines, including caffeine and pentoxifylline, are attractive candidates for drug repurposing, given their well-established safety and pharmacological profiles.
Anna Woziwodzka +6 more
doaj +1 more source
Molecules, 2023 A series of novel 1-N-α-d-glucopyranosyl-1H-1,2,3-triazole xanthines was synthesized from azido sugars (glucose, galactose, and lactose) and propargyl xanthines (theophylline and theobromine) using a typical copper (I)-catalyzed azide–alkyne 1,3-dipolar ...
Alma Sánchez-Eleuterio +9 more
doaj +1 more source
Metals, 2022 Metals stability and corrosion resistance are very important factors that influence the possibility of their applications. In order to study and foresee the behavior of metals during various applications in all kinds of conditions and media, numerous ...
Marija B. Petrović Mihajlović +4 more
doaj +1 more source
Pharmaceuticals, 2021 As life expectancy increases, dementia affects a growing number of people worldwide. Besides current treatments, phosphodiesterase 9 (PDE9) represents an alternative target for developing innovative small molecules to contrast neurodegeneration.
Giovanni Ribaudo +2 more
doaj +1 more source