Results 31 to 40 of about 8,048 (168)
Frontiers in Plant Science, 2023 The chemical composition, insect antifeedant, in vtro/in vivo nematicidal activity, phytotoxicity, and in silico nematicidal activity of the essential oil (EO) of the African medicinal plant Drypetes gossweileri were studied.
Jean Pierre Mbula +9 more
doaj +1 more source
Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review
Pharmacological Research, 2021 Benzyl isothiocyanate (BITC) is one of the common isothiocyanates found in cruciferous vegetables such as broccoli, cabbage or watercress. Preclinical studies report of its effectiveness in the prevention and treatment against several cancers. This review aims to report and discuss findings on anticancer activities of BITC and its modes of action ...
Thao Nhu, Dinh +3 more
openaire +2 more sources
Journal für Kulturpflanzen, 2009 Tropaeolum majus L. is a herb with antimicrobial activity in humans, caused by the degradation product benzyl-isothiocyanate derived from enzymatic cleavage of glucotropaeolin.
Elke Bloem +4 more
doaj +1 more source
The metabolism of benzyl isothiocyanate and its cysteine conjugate [PDF]
Biochemical Journal, 1977 1. The corresponding cysteine conjugate was formed when the GSH (reduced glutathione) or cysteinylglycine conjugates of benzyl isothiocyanate were incubated with rat liver or kidney homogenates. When the cysteine conjugate of benzyl isothiocyanate was similarly incubated in the presence of acetyl-CoA, the corresponding N-acetylcysteine conjugate ...
G, Brüsewitz +6 more
openaire +2 more sources
Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent [PDF]
Mutagenesis, 1999 Benzyl isothiocyanate (BITC) is contained in cruciferous plants which are part of the human diet. Numerous reports indicate that BITC prevents chemically induced cancer in laboratory animals and it has been postulated that BITC might also be chemoprotective in humans.
F, Kassie +3 more
openaire +2 more sources
Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Glutathione reductase (GR), an essential antioxidant enzyme against oxidative stress, has become an attractive drug target for the development of anticancer and antimalarial drugs.
Xia Li, Maowei Ni, Xiaoling Xu, Wei Chen
doaj +1 more source
Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells. [PDF]
PLoS ONE, 2012 Benzyl isothiocyanate (BITC), a constituent of edible cruciferous vegetables, inhibits growth of breast cancer cells but the mechanisms underlying growth inhibitory effect of BITC are not fully understood.
Dong Xiao +5 more
doaj +1 more source
In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. Numerous epidemiological studies have shown beneficial effects of cruciferous vegetables consumption in cancer chemoprevention.
Konić-Ristić Aleksandra +6 more
doaj +1 more source
Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity
Molecules, 2022 For decades, various plants have been studied as sources of biologically active compounds. Compounds with anticancer and antimicrobial properties are the most frequently desired.
Łukasz Janczewski
doaj +1 more source
Polarographic simultaneous determination of benzyl thiocyanate and benzyl isothiocyanate
BUNSEKI KAGAKU, 1973 有機チオシアネートおよびイソチオシアネート類としてベンジルチオシアネート(BTC)およびベンジルイソチオシアネート(BIT)を取り上げ,ポーラログラフ法により両者の同時定量を試みた.BTCおよびBITを含む試料液にn-ブチルアミンを添加し,BITを対応するチオウレア誘導体に変え,常法により直流ポーラログラムを記録し,チオウレア誘導体の酸化波とBTCの還元波より両者の分離定量を行なった.BTCおよびBITのそれぞれ1×10-3～1×10-4M範囲における検量線は直線性を示し,5×10-4Mにおける変動係数はBTCでは3.3%,BITでは2.2%であった.さらに本法をBTCの放射線分解物の分析に応用した.
Atsushi SUGII +3 more
openaire +2 more sources