Results 71 to 80 of about 448 (162)

Synthesis, characterization and in vitro evaluation of novel enantiomerically-pure sulphonamide antimalarials

, 2015
Malaria parasites are currently gaining drug-resistance rapidly, across countries and continents. Hence, the discovery and development of novel chemical scaffolds, with superior antimalarial activity remain an important priority, for the developing world.
Shivananju, NanjundaSwamy, Mathai, Jessin, Rangappa, K.S., Bender, A., Anusha, S., Anusha, Sebastian, Shivananju, N., Babu Rajeev, C. P., Bender, Andreas, Fuchs, J. E., Rangappa, K. S., Sinha, Ameya, Chandramohanadas, Rajesh, Basappa, S., Mathai, J., Chandramohanadas, R., Ximei, H., Chu, T. T. T., Preiser, Peter Rainer, Preiser, P. R., Chu, T.T.T., Shivananju, N. S., Sinha, A., Fuchs, J.E., Babu Rajeev, C.P., Preiser, P.R., Basappa, Rangappa, Kanchugarakoppal S., Huang, Ximei, Fuchs, Julian E., Rajeev, C. P. B., Chu, Trang T. T.   +31 more
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A simple randomized comparative study to evaluate the efficacy of 0.7% w/v Olopatadine hydrochloride ophthalmic solution and the Fixed Dose Combination of 0.1% w/v Olopatadine hydrochloride and 0.4% w/v Ketorolac tromethamine ophthalmic solution for the [PDF]

, 2019
Conjunctivitis is defined as the inflammation of the conjunctiva. Allergic conjunctivitis is an acute, intermittent or chronic inflammation of the conjunctiva due to air borne allergens.
Jagarlamudi, Anup, Harika, Soma, Rohit, Ch., Kavya Sri, K., Anushree, E.   +4 more
core   +1 more source

First report on green electrochemical sensing of bepotastine besilate based on tungsten doped vanadium dioxide nanoparticles: DFT assisted mechanistic insight

Journal of Saudi Chemical Society
A pioneering green electroanalytical sensor was introduced for a precise and environmentally considerate quantification of bepotastine besilate (BPST); a second-generation antihistaminic drug for treating allergic rhinitis and pruritus.
Aliyah S. Alhawiti, Bayan H. Alharbi, Amani Alhifthi, S. Alfadhli, Ahmed H. Jawhari, Razan M. Snari, Alaa A. Bahamran, Nashwa M. El-Metwaly   +7 more
doaj   +1 more source

The crystal structure of bepotastine besilate, C27H31ClN2O6S

Zeitschrift für Kristallographie - New Crystal Structures
C27H31ClN2O6S, triclinic, P1 (no. 1), a = 8.0223(3) Å, b = 9.8143(3) Å, c = 10.2307(4) Å, α = 88.308(3)°, β = 69.000(3)°, γ = 65.970(3)°, V = 680.39(5) Å3, Z = 1, R gt(F) = 0.0406, wRref (F 2) = 0.1165, T = 297 K.
Wang Fengfeng, Luan Lin, Hu Xiaowen, Zhang Caiyu, Liu Yang   +4 more
doaj   +1 more source

Design and Evaluation of Ophthalmic Delivery of Bepotastine Besilate From Eye Drop

Pharmaceutical Methods, 2016
Introduction: The purpose of present study was to design and evaluate bepotastine besilate ophthalmic solution 1.5% to develop a stable formulation using buffering agent, tonicity modifier and preservative. Method: In this study the concentration of preservative and tonicity modifier concentration are adjusted in such a way so that the final ...
Askarkar, Sonali Suresh, Gupta, Krishna Radheshyam   +1 more
openaire   +2 more sources

Stability Indicating Chromatographic Method For Estimation Of Bepotastine Besilate

, 2018
A Simple, rapid, stability indicating HPTLC method has been developed for estimation of bepotastine besilate. HPTLC separation was carried out on Merck TLC aluminium sheets precoated with silica gel 60F254 using mobile phase as chloroform : methanol. Bepotastine besilate gave sharp peak at RF 0.53 ±0.03 at 225nm.calibration curve was linear in range 5 ...
openaire   +2 more sources

Effects of second generation antihistamines on daily driving with and without subtasks measured in a driving simulator

Discover Applied Sciences
Background Second-generation antihistamines are widely used for the management of allergic conditions. In addition, many second-generation antihistamines are readily available over the counter at pharmacies.
Akihito Nagahama, Atsunobu Sagara, Hayato Aki, Hiroki Yoshimura, Makoto Hiraide, Takatsune Shimizu, Motohiko Sano, Tetsuro Yumoto, Tomoo Hosoe, Kenji Tanaka   +9 more
doaj   +1 more source

Pharmacokinetic Characteristics of Bepotastine Besilate in Healthy Subjects [PDF]

Journal of Korean Society for Clinical Pharmacology and Therapeutics, 2007
Bo-Hyung Kim, Jae-Yong Chung, Jung-Ryul Kim, Kyoung Soo Lim, Hyeong-Seok Lim, Kyung-Sang Yu, In-Jin Jang, Sang-Goo Shin   +7 more
openaire   +1 more source

Clinical Study Concentrations of H1-Receptor Antagonist in the Human Nasal Mucosa

, 2009
Aims. To measure blood and tissue concentrations of the H1-receptor antagonist, bepotastine besilate (BB). Methods. Participants included 14 men and six women, whose age ranged from 13 to 76 years, with chronic rhinosinusitis, who underwent endoscopic ...
Haruo Takahashi, Kenji Takasaki, Kaori Enatsu, Hidetaka Kumagami   +3 more
core  

Brain Histamine H1 Receptor Occupancy of Antihistamines, Bepotastine and Diphenhydramine, Measured by [11C]Doxepin PET [PDF]

, 2011
紀要類 (bulletin)departmental bulletin ...
Kato, M., Watanuki, S., Funaki, Y., Tashiro, M., Ishikawa, S., Duan, X., Iwata, R., Itoh, M., Yanai, K., Miyake, M.   +9 more
core   +1 more source