The Effect of Prophylactic Treatment with Bepotastine in Patients with Japanese Cedar Pollinosis.
The clinical effect of Bepotastine in patients with Japanese cedar allergy was investigated before and after the start of the pollen season. Symptom score, medication score and symptom-medication score were significantly lower in patients treated before the pollen season than in those treated after it started.These results indicate that Bepotastine is ...
OHTA, Nobuo +7 more
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The crystal structure of bepotastine besilate, C27H31ClN2O6S
C27H31ClN2O6S, triclinic, P1 (no. 1), a = 8.0223(3) Å, b = 9.8143(3) Å, c = 10.2307(4) Å, α = 88.308(3)°, β = 69.000(3)°, γ = 65.970(3)°, V = 680.39(5) Å3, Z = 1, R gt(F) = 0.0406, wRref (F 2) = 0.1165, T = 297 K.
Wang Fengfeng +4 more
doaj +1 more source
Design and Evaluation of Ophthalmic Delivery of Bepotastine Besilate From Eye Drop
Introduction: The purpose of present study was to design and evaluate bepotastine besilate ophthalmic solution 1.5% to develop a stable formulation using buffering agent, tonicity modifier and preservative. Method: In this study the concentration of preservative and tonicity modifier concentration are adjusted in such a way so that the final ...
Askarkar, Sonali Suresh +1 more
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Background: Pharmacotherapy is the mainstay of allergic rhinitis and many caregivers use over-the-counter antihistamines. Bepotastine is a novel oral second generation non-sedative antihistamine and an effective treatment option for allergic rhinitis.
A. T. Priyanka +2 more
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Background Second-generation antihistamines are widely used for the management of allergic conditions. In addition, many second-generation antihistamines are readily available over the counter at pharmacies.
Akihito Nagahama +9 more
doaj +1 more source
Stability Indicating Chromatographic Method For Estimation Of Bepotastine Besilate
A Simple, rapid, stability indicating HPTLC method has been developed for estimation of bepotastine besilate. HPTLC separation was carried out on Merck TLC aluminium sheets precoated with silica gel 60F254 using mobile phase as chloroform : methanol. Bepotastine besilate gave sharp peak at RF 0.53 ±0.03 at 225nm.calibration curve was linear in range 5 ...
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Pharmacokinetic Characteristics of Bepotastine Besilate in Healthy Subjects [PDF]
Bo-Hyung Kim +7 more
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To compare efficacy of bepotastine besilate (1.5%) versus alcaftadine (0.25%) in patients with vernal keratoconjunctivitis.This comparative, randomized, single-blind and prospective study was conducted on 100 patients diagnosed with VKC, who were allocated to receive either of the two treatment groups.
Neha Yadav +5 more
openaire +1 more source
Exploring the interactions of antihistamine with retinoic acid receptor beta (RARB) by molecular dynamics simulations and genome-wide meta-analysis. [PDF]
Kim MJ +3 more
europepmc +1 more source
Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial. [PDF]
Kitahiro Y +20 more
europepmc +1 more source

