Results 61 to 70 of about 428 (162)

Improvement of Dupilumab‐Induced Psoriasiform Eruption Following a Switch to Tralokinumab

open access: yesJEADV Clinical Practice, Volume 4, Issue 5, Page 1210-1215, December 2025.
ABSTRACT Biologic therapies have transformed the management of atopic dermatitis (AD) and prurigo nodularis (PN), yet paradoxical adverse events such as dupilumab‐induced psoriasiform eruption (DPE) are increasingly recognized. We report a 48‐year‐old Japanese man with long‐standing AD and PN who developed scaly, erythematous plaques on the elbows ...
Masato Mizuashi, Yoshinori Sasaki
wiley   +1 more source

Comparative efficacy of bepotastine besilate 1.5% ophthalmic solution versus olopatadine hydrochloride 0.2% ophthalmic solution evaluated by patient preference

open access: yesClinical Ophthalmology, 2012
Craig F McCabe, Shannon E McCabeMcCabe Vision Center, Murfreesboro, TN, USABackground: The aim of this study was to compare patient-perceived relief of ocular itch, nasal symptoms, and eye drop comfort when allergic conjunctivitis was treated with ...
McCabe CF, McCabe SE
doaj  

Tunable Preparation of α‐Aminoacyl Fluorides and α‐Fluoroamides via Base‐Induced Cascade Multiple‐Cleavage Processes from Bromodifluorohydrin Reagents and Amines

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 17, September 26, 2025.
A mild and versatile strategy enabling the divergent synthesis of α‐fluoroamides and α‐aminoacyl fluorides from 2‐bromo‐2,2‐difluoro alcohols and amines is developed. The reaction shows broad scope and operational simplicity. Mechanistic and density functional theory studies support the formation of a putative gem‐difluoroepoxide intermediate ...
Giulia De Santis   +8 more
wiley   +1 more source

Immediate Clinical Effectiveness of Bepotastine Besilate for Patients with Urticaria

open access: yesNishi Nihon Hifuka, 2006
蕁麻疹患者25例を対象として,ベシル酸ベポタスチン錠(タリオン®錠)の即効性と有用性に関するアンケート調査を行なった。即効性(内服後痒みの抑制効果を自覚した時間)に関しては回答を得た20例で,全例が内服後90分以内に痒みの抑制効果を自覚していた(内服後30分以内が50%,内服後60分以内が89%)。また92%以上が何らかの有効性を自覚していた。効果の持続時間に関しては,回答を得た19例で,4時間が16%,8時間32%,12時間が47%という結果であった。眠気の副作用は33%に認められたが,84%の患者は再処方を希望したことから,本剤の高い有用性が示された。
KOHDA, Futoshi   +2 more
openaire   +1 more source

Treatment of atopic dermatitis: Recently approved drugs and advanced clinical development programs

open access: yesAllergy, Volume 79, Issue 6, Page 1501-1515, June 2024.
Abstract Atopic dermatitis (AD) represents the most common skin disease characterized by heterogeneous endophenotypes and a high disease burden. In Europe, six new systemic therapies for AD have been approved: the biologics dupilumab (anti‐interleukin‐4 receptor (IL‐4R) α in 2017), tralokinumab (anti‐IL‐13 in 2021), lebrikizumab (anti‐IL‐13 in 2023 ...
Svenja Müller   +2 more
wiley   +1 more source

Figure S1 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts

open access: yes, 2023
Figure S1, related to Fig ...
Ping Jin (15063054)   +13 more
core   +2 more sources

A study on the clinical presentations and treatment response to different therapies in seasonal allergic conjunctivitis

open access: yesJournal of Clinical Ophthalmology and Research
Purpose: The purpose is to study the clinical presentation of seasonal allergic conjunctivitis (SAC) and treatment response to different therapies. Methods: This hospital-based comparative study included all patients aged over 10 years old diagnosed with
Srilekha Berelli   +2 more
doaj   +1 more source

Orofacial Granulomatosis among Pediatric Patients Well Controlled by Corticosteroid Treatment: A Rare Case Series

open access: yesCase Reports in Pediatrics, Volume 2024, Issue 1, 2024.
Orofacial granulomatosis (OFG) is a rare disease entity characterized by nonnecrotizing granulomatous inflammation in the oral and maxillofacial regions, typically characterized by recurrent or persistent edema, primarily in the lips and occasionally in the gingiva. OFG is often associated with Crohn’s disease and sarcoidosis, and an accurate diagnosis
Taku Kimura   +7 more
wiley   +1 more source

Evaluation of Efficacy and Sedative Profiles of H1 Antihistamines by Large-Scale Surveillance Using the Visual Analogue Scale (VAS)

open access: yesAllergology International, 2008
Background: H1 antihistamines are widely used as therapeutics for allergic diseases. Sedation is a well-known side effect of H1 antihistamines and sometimes it is life-threatening for patients.
Norimasa Izumi   +4 more
doaj   +1 more source

Figure S4 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts

open access: yes, 2023
Figure S4, related to Fig ...
Ping Jin (15063054)   +13 more
core   +2 more sources

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