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Integrated Metabolomics and Transcriptomics Analysis Reveals the Biosynthetic Mechanism of Isoquinoline Alkaloids in Different Tissues of <i>Hypecoum erectum</i> L. [PDF]

Curr Issues Mol Biol
Wang S, Du Y, Yang M.
europepmc   +1 more source

Eight Triplex-Binding Molecules from Four Chemical Classes Broadly Recognize the MALAT1 Triple Helix. [PDF]

Molecules
Mousseau MM, Shivakumar KM, Yoo J, Brown JA.   +3 more
europepmc   +1 more source

Exploring the anticancer potential of <i>Tinospora cordifolia</i> with computational insights into EGFR inhibition. [PDF]

In Silico Pharmacol
Asha G, Lekshmi S, Najmathunnisa KP, Rajva T, Krishnakumar V, Hussan KPS.   +5 more
europepmc   +1 more source

A review on analytical methods for natural berberine alkaloids

Journal of Separation Science, 2019
AbstractBerberine alkaloids, a group of protoberberine alkaloids under the classification of isoquinoline alkaloids, include berberine, coptisine, palmatine, columbamine, dehydrocorydaline, jatrorrhizine, and epiberberine from natural sources. Studies have shown that berberine alkaloids have various pharmacological functions, such as antibacterial ...
Bing Wang
exaly   +4 more sources

Structural modification of berberine alkaloids in relation to cytotoxic activity in vitro

Journal of Ethnopharmacology, 2000
The cytotoxicity of two protoberberine alkaloids: berberine and lincangenine, their 8-hydroxy-7,8-dihydro-derivatives and tetrahydroprotoberberine:thaicanine, was evaluated. The cellular responses through the [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide] (MTT) method were measured in Hela (uterus carcinoma), SVKO3 (ovary carcinoma),
FRANCISCO Arvelo
exaly   +4 more sources

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Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

European Journal of Medicinal Chemistry, 2021
Alkaloids are one of the most important classes of plant bioactives. Among these isoquinoline alkaloids possess varied structures and exhibit numerous biological activities. Basically these are biosynthetically produced via phenylpropanoid pathway. However, occasionally some mixed pathways may also occur to provide structural divergence.
Sneha Singh, Arvind S Negi
exaly   +3 more sources