Results 121 to 130 of about 56,924 (160)

A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC. [PDF]

Proc Natl Acad Sci U S A
Guo J, Li K, Ming Y, Pan Y, Tan S, Ma H, Chen S, Duan Y, Peng Y.   +8 more
europepmc   +1 more source

Epigenetic targeting of Waldenström macroglobulinemia cells with BET inhibitors synergizes with BCL2 or histone deacetylase inhibition. [PDF]

Epigenomics, 2021
Matissek SJ, Han W, Karbalivand M, Sayed M, Reilly BM, Mallat S, Ghazal SM, Munshi M, Yang G, Treon SP, Walker SR, Elsawa SF.   +11 more
europepmc   +1 more source

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation. [PDF]

Blood
Shah V, Giotopoulos G, Osaki H, Meyerhöfer M, Meduri E, Gallego-Crespo A, Behrendt MA, Saura-Pañella M, Tarkar A, Schubert B, Yun H, Horton SJ, Agrawal-Singh S, Haehnel PS, Basheer F, Lugo D, Eleftheriadou I, Barbash O, Dhar A, Kühn MWM, Guezguez B, Theobald M, Kindler T, Gallipoli P, Yeh P, Dawson MA, Prinjha RK, Huntly BJP, Sasca D.   +28 more
europepmc   +1 more source

CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway. [PDF]

Cancer Drug Resist
Gu J, Dai Z, Shen T, Chen X, Yang Z, Sun S, Chen D, Luo H, Wang X, Xu J.   +9 more
europepmc   +1 more source

BCL6 confers KRAS-mutant non-small-cell lung cancer resistance to BET inhibitors. [PDF]

J Clin Invest, 2021
Guo J, Liu Y, Lv J, Zou B, Chen Z, Li K, Feng J, Cai Z, Wei L, Liu M, Pang X.   +10 more
europepmc   +1 more source

Elastase and its Inhibitors in Intensive Care Medicine [PDF]

, 1990
Fritz, Hans, Jochum, Marianne
core   +1 more source

The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53. [PDF]

Neoplasia, 2021
Yi JS, Sias-Garcia O, Nasholm N, Hu X, Iniguez AB, Hall MD, Davis M, Guha R, Moreno-Smith M, Barbieri E, Duong K, Koach J, Qi J, Bradner JE, Stegmaier K, Weiss WA, Gustafson WC.   +16 more
europepmc   +1 more source

Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells. [PDF]

Mol Ther Nucleic Acids, 2021
Liu C, Gen Y, Tanimoto K, Muramatsu T, Inoue J, Inazawa J.   +5 more
europepmc   +1 more source

BET inhibitors (BETi) influence oxidative phosphorylation metabolism by affecting mitochondrial dynamics leading to alterations in apoptotic pathways in triple-negative breast cancer (TNBC) cells. [PDF]

Cell Prolif
Rossi T, Iorio E, Chirico M, Pisanu ME, Amodio N, Cantafio MEG, Perrotta I, Colciaghi F, Fiorillo M, Gianferrari A, Puccio N, Neri A, Ciarrocchi A, Pistoni M.   +13 more
europepmc   +1 more source

BET inhibitors drive Natural Killer activation in non-small cell lung cancer via BRD4 and SMAD3. [PDF]

Nat Commun
Reggiani F, Talarico G, Gobbi G, Sauta E, Torricelli F, Manicardi V, Zanetti E, Orecchioni S, Falvo P, Piana S, Lococo F, Paci M, Bertolini F, Ciarrocchi A, Sancisi V.   +14 more
europepmc   +1 more source