Results 271 to 275 of about 24,956 (275)

Naphthyridines as Novel BET Family Bromodomain Inhibitors

ChemMedChem, 2014
Olivier Mirguet, Chun-Wa Chung, Paul Bamborough   +2 more
exaly  

Exploiting the 7-methylimidazo[1,5-a]pyrazin-8(7H)-one scaffold for the development of novel chemical inhibitors for Bromodomain and Extraterminal Domain (BET) family

Bioorganic Chemistry, 2019
Leilei Zhao, Changliang Xu, Jinpei Zhou   +2 more
exaly  

PROTAC BET degraders are more broadly effective than BET inhibitors

European Journal of Cancer, 2016
J. Winkler, K. Raina, M. Altieri, H. Dong, J. Wang, X. Chen, A. Crew, C. Crews, Y. Qian, R. Kleinfield, K. Coleman   +10 more
openaire   +1 more source

Investigational BET bromodomain protein inhibitors in early stage clinical trials for acute myelogenous leukemia (AML)

Expert Opinion on Investigational Drugs, 2017
Claude Gardin
exaly  

Betting on β-catenin inhibitors in oncology

Nature Reviews Drug Discovery
openaire   +1 more source