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Small-Molecule Targeting of BET Proteins in Cancer
2016BET proteins have recently become recognized for their role in a broad range of cancers and are defined by the presence of two acetyl-histone reading bromodomains and an ET domain. This family of proteins includes BRD2, BRD3, BRD4, and BRDT. BRD4 is the most-studied BET protein in cancer, and normally serves as an epigenetic reader that links active ...
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Lhasa Proteins Try, but Only T-bet Matters
Science Signaling, 2000Naïve T helper lymphocytic cells differentiate into Th1 and Th2 cells, and they are defined by the cytokines they produce. The transcription factors GATA-3 and c-Maf are important for Th2 differentiation, but the components that cause Th1 differentiation are less well defined. Szabo et al .
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
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Killing pluripotent stem cells by BET protein inhibition
Science Bulletin, 2018Shufeng, Ma, Ying, Lin, Zhili, Rong
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[Anaphylaxis to PR-10 proteins (Bet v1 homologues)].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2014Secondary food allergies to PR-10 proteins (Bet v1 homologues) are the most common food allergies in Germany. Clinically they present with an oral allergy syndrome (intraoral pruritus and perhaps swelling). When drinks containing PR-10 proteins are rapidly consumed, for example after sporting activities, large concentrations of allergen can be reached ...
S, Röseler +6 more
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[The research progress of foamy virus Bet protein].
Bing du xue bao = Chinese journal of virology, 2012Foamy virus can establish lifelong persistent infection in mammal hosts without inducing diseases. Such special characteristic stimulates the interests of researchers. As reported, the accessory protein Bet of foamy virus could regulate the gene expression and infection cycle of foamy virus and take part in the generation of chronic viral infection ...
Yuan, Gao +5 more
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Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
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