Results 51 to 60 of about 157,278 (142)

Immunoinformatics-guided design of a multiepitope peptide vaccine targeting the receptor-binding domain of SARS-CoV-2 spike glycoprotein: insights from Indonesian samples

Journal of Integrative Bioinformatics
The emergence of new variants of SARS-CoV-2, including Alpha, Beta, Gamma, Delta, Omicron variants, and XBB sub-variants, contributes to the number of coronavirus cases worldwide.
Faizal Irvan, Chandra Darrian, Tarwadi, Pambudi Sabar, Nurhasanah Astutiati, Priambodo Rizky, Yusuf Muhammad   +6 more
doaj   +1 more source

Anti-phospholipid syndrome in seven leprosy patients with thrombotic events on corticosteroid and/or thalidomide regimen: insights on genetic and laboratory profiles

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Corticosteroids and/or thalidomides have been associated with thromboembolism events (TBE) in multibacillary (MB) leprosy. This report aimed to determine genetic and laboratory profiles associated with leprosy and TBE.
Sebastian Vernal, Maria Jose Franco Brochado, Roberto Bueno-Filho, Paulo Louzada-Junior, Ana Maria Roselino   +4 more
doaj   +1 more source

Interaction of the antiphospholipid syndrome autoantigen beta-2 glycoprotein I with DNA and neutrophil extracellular traps. [PDF]

Clin Immunol, 2023
Kmeťová K, Lonina E, Yalavarthi S, Levine JS, Hoy CK, Sarosh C, Gockman K, Morris AE, Tambralli A, Madison JA, Zuo Y, Subang R, Rauch J, Knight JS.   +13 more
europepmc   +1 more source

Lysine residues control the conformational dynamics of beta 2-glycoprotein I

Physical Chemistry Chemical Physics, 2018
We report on a strategy to permanently open up the closed conformation of soluble blood protein beta 2-glycoprotein I by chemical acetylation of lysine residues.
Ina Buchholz, Peter Nestler, Susan Köppen, Mihaela Delcea   +3 more
openaire   +4 more sources

Pharmacogenetics of antidepressants

Frontiers in Pharmacology, 2011
Up to 60% of depressed patients do not respond completely to antidepressants (AD) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes
Concetta eCrisafulli, Chiara eFabbri, Stefano ePorcelli, Antonio eDrago, Edoardo eSpina, Diana eDe Ronchi, Alessandro eSerretti   +6 more
doaj   +1 more source

Anticardiolipin and anti-beta 2-glycoprotein I antibodies in patients with unexplained articular manifestations. [PDF]

J Clin Lab Anal, 2023
Melayah S, Ghozzi M, Ghedira I, Mankaï A.   +3 more
europepmc   +1 more source

Anticardiolipin and anti-beta-2 glycoprotein I antibodies in patients with moderate or severe COVID-19. [PDF]

Am J Med Sci, 2023
Garcia-Arellano G, Camacho-Ortiz A, Moreno-Arquieta IA, Cardenas-de la Garza JA, Rubio-Torres DC, Garza-Gonzalez E, Bocanegra-Ibarias P, Galarza-Delgado DA.   +7 more
europepmc   +1 more source

IgA anti-β2-glycoprotein I as an independent risk factor in acute venous thromboembolism

Frontiers in Immunology
BackgroundVenous thromboembolism (VTE) is the third most common cause of cardiovascular death. Primary Antiphospholipid Syndrome (P-APS) is a chronic systemic autoimmune disorder characterized by thrombotic events and/or obstetric complications in ...
Raquel Diaz-Simon, Raquel Diaz-Simon, Raquel Diaz-Simon, Antonio Lalueza, Antonio Lalueza, Antonio Lalueza, Manuel Serrano, Manuel Serrano, Manuel Serrano, Manuel Serrano, Daniel Pleguezuelo, Daniel Pleguezuelo, Oscar Cabrera-Marante, Oscar Cabrera-Marante, Oscar Cabrera-Marante, Oscar Cabrera-Marante, David Lora, Carmen Diaz-Pedroche, Carmen Diaz-Pedroche, Covadonga Gomez-Cuervo, Asunción Perez-Jaicoste, Asunción Perez-Jaicoste, Sara Garcinuño, Sara Garcinuño, Laura Naranjo, Elena Martinez-Chamorro, Elena Martinez-Chamorro, Yolanda Revilla-Ostolaza, Estela Paz-Artal, Estela Paz-Artal, Estela Paz-Artal, Estela Paz-Artal, Carlos Lumbreras-Bermejo, Carlos Lumbreras-Bermejo, Antonio Serrano   +34 more
doaj   +1 more source

Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy

EMBO Molecular Medicine, 2017
Lentiviral vectors (LV) are powerful and versatile vehicles for gene therapy. However, their complex biological composition challenges large‐scale manufacturing and raises concerns for in vivo applications, because particle components and contaminants ...
Michela Milani, Andrea Annoni, Sara Bartolaccini, Mauro Biffi, Fabio Russo, Tiziano Di Tomaso, Andrea Raimondi, Johannes Lengler, Michael C Holmes, Friedrich Scheiflinger, Angelo Lombardo, Alessio Cantore, Luigi Naldini   +12 more
doaj   +1 more source

The morphology of porcine oocytes is associated with zona pellucida glycoprotein 3 and integrin beta 2 protein levels--

Veterinární Medicína, 2010
The morphology and quality of oocytes is set during oo- and folliculo-genesis, and is completed during final maturation. Early embryonic development is associated with the morphology of the cumulus-oocyte-complex (COC).
P. Antosik, B. Kempisty, M. Jackowska, D. Bukowska, M. Lianeri, K.P. Brussow, M. Wozna, J.M. Jaskowski   +7 more
doaj   +1 more source