Results 151 to 160 of about 61,745 (283)

Berberine ameliorates acute hyperglycemia and hypoinsulinemia induced by ketamine/xylazine in rats: role of alpha₂ adrenergic receptors, oxidative stress and inflammatory suppressing mechanisms. [PDF]

BMC Vet Res
Kadhim RA, Erfanparast A, Tamaddonfard E, Amirkashani D, Imani M.   +4 more
europepmc   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Cirrhotic Cardiomyopathy: Bridging Hepatic and Cardiac Pathophysiology in the Modern Era. [PDF]

J Clin Med
Lupu D, Scârneciu CC, Țînț D, Tudoran C.   +3 more
europepmc   +1 more source

Rapidly Fatal Multiple Organ Failure of Intravenous Amiodarone: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 10, October 2025.
This graphical abstract illustrates the diagnostic journey of a 75‐year‐old male with severe coughing, breathing difficulties, using the patient's electrocardiogram (ECG) recordings as the pivotal clue for identifying atrial flutter with rapid ventricular response.
BinYu, Hongyan Li, Xiongying Chen
wiley   +1 more source

MAPK, PI3K/Akt Pathways, and GSK-3β Activity in Severe Acute Heart Failure in Intensive Care Patients: An Updated Review. [PDF]

J Cardiovasc Dev Dis
Meco M, Giustiniano E, Nisi F, Zulli P, Agosteo E.   +4 more
europepmc   +1 more source

cAMP-dependent protein kinase and protein kinase C consensus site mutations of the beta-adrenergic receptor. Effect on desensitization and stimulation of adenylylcyclase.

, 1994
N. Yuan, Jacqueline Friedman, Brenda S. Whaley, R B Clark   +3 more
openalex   +1 more source

DNA‐mediated UCP1 overexpression in adipose tissue: A promising anti‐obesity gene therapy

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
This study developed a weight loss gene therapy targeting adipose tissue, which achieved adipose‐specific overexpression of UCP1 by modifying plasmids. This gene therapy strategy achieves adipose‐selective overexpression of UCP1 protein and induces adipose thermogenesis, leading to reduced weight gain, improved metabolic homeostasis, and enhanced ...
Ze‐Wei Zhao, Longyun Hu, Bigui Song, Qian Wu, Jiejing Lin, Qingqing Liu, Siqi Liu, Jin Li, Molin Wang, Jin Li, Zhonghan Yang   +10 more
wiley   +1 more source

Multi-region mapping of ligand binding and structural changes in the β-1 adrenergic receptor using carbene footprinting and mass spectrometry. [PDF]

Chem Sci
Lloyd JR, Varughese AS, Kapoor P, Dürr KL, Yen HY, Jazayeri A, Hopper JTS, Oldham NJ.   +7 more
europepmc   +1 more source

An approach to the study of G-protein-coupled receptor kinases: an in vitro-purified membrane assay reveals differential receptor specificity and regulation by G beta gamma subunits.

Proceedings of the National Academy of Sciences of the United States of America, 1994
G. Pei, M. Tiberi, M. Caron, R. Lefkowitz   +3 more
semanticscholar   +1 more source

Synergistic Effects of Bioactive Compounds on Human Adiposity Mechanisms of Fat Loss and Fat Accumulation

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Chronic diseases are associated with imbalances in adipose tissue, which plays a crucial role in regulating metabolic health. Food‐based bioactive substances (such as polyphenols, terpenoids, peptides, and fibers) impact fat metabolism by influencing the processes of lipolysis, adipogenesis, thermogenesis, and appetite control.
Mohamed Ibrahim Younis, Rawaa H. Tlay, Ammar B. Altemimi, Zheng Ruan, Tarek Gamal Abedelmaksoud   +4 more
wiley   +1 more source