Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells
Advanced Materials, EarlyView.This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park +13 more
wiley +1 more source
Evaluating the effectiveness of alternative treatments for menopausal symptoms in postmenopausal women [PDF]
Гинекология, 2017 Purpose of the study - to evaluate the effectiveness of black cohosh extract (Chi-Klim drug) and its combination with beta-alanine (Chi-Klim Alanine) for the treatment of menopausal symptoms in women in the early and late postmenopausal women.
S V Yureneva, E I Ermakova
doaj
Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia- reperfusion injury. [PDF]
Cardiovasc Res, 2022 Harris M +10 more
europepmc +1 more source
Response to comments on the Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on the scientific substantiation of a health claim related to beta‐alanine and increased physical performance during short‐duration, high‐intensity exercise pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
, 2015 European Food Safety Authority (EFSA)
openalex +1 more source
Advanced Materials, EarlyView.The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source
Advanced Materials, EarlyView.Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Advanced Robotics Research, EarlyView.To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang +9 more
wiley +1 more source
The Effects of a Commercial, Pre-exercise Energy Drink Supplement on Power, Muscular Endurance, and Repeated Sprint Speed [PDF]
, 2016 International Journal of Exercise Science 9(2): 205-213, 2016. The purpose of this study was to investigate the effects of ingesting a pre-workout commercial energy drink supplement on multiple parameters of physical performance, including upper body and
Campbell, Bill I +2 more
core +1 more source
Ice Recrystallization Inhibition by Amino Acids: The Curious Case of Alpha- and Beta-Alanine. [PDF]
J Phys Chem Lett, 2022 Warren MT +4 more
europepmc +1 more source
Advanced Synthesis &Catalysis, EarlyView.We show how engineered ancestral amide bond synthetases (ABSs) together with cofactor recycling using a single polyphosphate kinase paves the way for chemoenzymatic synthesis of pharmacophores. The figure illustrates how ancestral ABS has a more flexible C‐terminal domain, which is associated with enhanced catalytic performance and expanded amine scope.
Elisabeth Söderberg +5 more
wiley +1 more source