Results 221 to 230 of about 1,107,155 (284)

Crocetin inhibits beta-amyloid fibrillization and stabilizes beta-amyloid oligomers

Biochemical and Biophysical Research Communications, 2011
Aggregation of a peptide, beta-amyloid (Aβ), is a hallmark molecular process found in Alzheimer's disease (AD). During Aβ aggregation, oligomeric and fibrillar Aβ are formed, and these molecular self-assembly steps are implicated in generation of toxic effects in AD.
Joon Ho, Ahn, Yang, Hu, Michael, Hernandez, Jin Ryoun, Kim   +3 more
openaire   +2 more sources

Clearance of Beta-Amyloid in the Brain

Current Medicinal Chemistry, 2014
Intravascular substances invade extracellular spaces in the brain via endothelial cells in the sites without bloodbrain barrier (BBB) and move not only in the cerebrospinal fluid (CSF) but also in the interstitial fluid (ISF) of brain parenchyma adjacent to non-BBB sites.
Masaki, Ueno, Yoichi, Chiba, Koichi, Matsumoto, Toshitaka, Nakagawa, Hiroshi, Miyanaka   +4 more
openaire   +2 more sources

Beta-amyloid immunisation in Alzheimer’s disease

Neurological Sciences, 2005
Beta-amyloid immunisation in Alzheimer's ...
openaire   +2 more sources