Results 121 to 130 of about 1,106,914 (319)

Nuclear hormone receptor LXRα inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling [PDF]

, 2015
Kenichi Matsushita, Fulvio Morello, Zhiping Zhang, Tomoko Masuda, Shiro Iwanaga, Knut R. Steffensen, Jan-Ακε Gustafsson, Richard E. Pratt, Victor J. Dzau   +8 more
openalex   +1 more source

Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer [PDF]

, 2020
Suzy Scholl, Jonas Béal, Leanne de Koning, Elodie Girard, Marina Popović, Anne de la Rochefordière, Fabrice Lécuru, Virginie Fourchotte, Charlotte Ngô, Anne Floquet, Els M.J.J. Berns, Gemma G. Kenter, Pierre Gestraud, Heiko von der Leyen, Charlotte Lecerf, Vincent Puard, Sergio Roman‐Roman, Aurélien Latouche, Attila Kereszt, Balázs Bálint, Roman Rouzier, Maud Kamal   +21 more
openalex   +1 more source

Ethacrynic Acid Enhances the Antitumor Effects of Afatinib in EGFR/T790M-Mutated NSCLC by Inhibiting WNT/Beta-Catenin Pathway Activation [PDF]

, 2021
Xuehui Zhang, Chaoyuan Huang, Bi-Yu Cui, Ye-Bin Pang, Rong Liang, Xiaoling Luo   +5 more
openalex   +1 more source

Wnt/beta-catenin signaling: components, mechanisms, and diseases.

Developmental Cell, 2009
Bryan T. MacDonald, K. Tamai, Xi He
semanticscholar   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.

Proceedings of the National Academy of Sciences of the United States of America, 1999
M. Shtutman, J. Zhurinsky, I. Simcha, C. Albanese, M. D’Amico, R. Pestell, A. Ben-Ze'ev   +6 more
semanticscholar   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors.

Cancer Treatment Reviews, 2018
Nithya Krishnamurthy, R. Kurzrock
semanticscholar   +1 more source

Beta-catenin in the melanocyte lineage.

Pigment cell research, 2004
beta-Catenin is a multifunctional protein involved in cell-cell adhesion, intracellular signalling and gene transcription. It has been implicated in the development of various lineages, including neural crest derivatives. Melanocytes are derived from neural crest cells and beta-catenin is expressed throughout the development of this cell lineage.
Larue, L, Kumasaka, M, Goding, C
openaire   +2 more sources