Results 191 to 200 of about 574,698 (305)

Improvement of Mouse Spermatozoa Freezing at ‐80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

Andrology, EarlyView.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso, Renata Paoletti, Simone Cassetti, Nicola Bernabò, Barbara Barboni, Marcello Raspa, Ferdinando Scavizzi   +6 more
wiley   +1 more source

DNA as Drug Carrier: A Hydrophobic β-Cyclodextrin Channel in a Supramolecular Structure. [PDF]

Chemistry
Raffaini G.
europepmc   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Improving in vitro Gastrointestinal Stability of Phlorotannins From Food Grade Fucus vesiculosus Extracts Using Cyclodextrins. [PDF]

J Food Sci
Reis SF, Catarino MD, Braga SS, Coimbra MA, Silva AMS, Cardoso SM.   +5 more
europepmc   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Radiolabelled Cyclodextrins for the Positron Emission Tomography Imaging of Breast Cancer: Preclinical Perspectives. [PDF]

Clin Transl Sci
Sass T, Szabó JP, Dienes RA, Árkosy P, Opposits G, Jószai I, Fekete A, Fenyvesi F, Hajdu I, Trencsényi G, Képes Z.   +10 more
europepmc   +1 more source

A Zeolitic Pyrimidine Framework (ZPF) Nanoplatform Co‐Delivers a DNAzyme and a Protein Prodrug for Cascade‐Activated Tumour Therapy

Cell Proliferation, EarlyView.
A zeolitic framework co‐delivers a DNAzyme and a protein prodrug to tumour cells and executes a self‐amplifying therapeutic cascade: the DNAzyme elevates tumour oxidative stress to activate a caged RNase A prodrug. This spatiotemporally controlled synergy converts a genetic input into potent enzymatic cytotoxicity, suppressing tumour growth.
Yan Huang, Xingjie Hu, Jinli Sun, Min Yin, Nan Chen   +4 more
wiley   +1 more source

Cyclodextrins in action: Modulating <i>candida albicans</i> biofilm formation and morphology. [PDF]

Biotechnol Rep (Amst)
Márton R, Hermann H, Kiss VT, Fenyvesi É, Szente L, Molnár M.   +5 more
europepmc   +1 more source

Characterization, antifungal potential, cytocompatibility, and regenerative potential of mucoadhesive gel containing antifungal‐β‐cyclodextrin inclusion complexes

Journal of Prosthodontics, EarlyView.
Abstract Purpose This study aimed to characterize a mucoadhesive gel containing nystatin (NYS) or chlorhexidine (CHX), complexed or not with β‐cyclodextrin (βCD), and evaluate its rheological and mucoadhesive properties, antifungal efficacy, cytocompatibility, and collagen synthesis potential.
Carolina Yoshi Campos Sugio, Amanda Aparecida Maia Neves Garcia, Diana Gabriela Soares, Fernanda Balestrero Cassiano, Marcela Alves de Mattos, Simone Soares, Priscileila Colerato Ferrari, Maria Helena Fernandes, Vanessa Migliorini Urban, Karin Hermana Neppelenbroek   +9 more
wiley   +1 more source

Mitigating Mucoadhesion of β-Cyclodextrins via PEGylation: Insights from ¹⁹F Diffusion NMR Analysis. [PDF]

Int J Mol Sci
Nguyen KTH, Ba Y.
europepmc   +1 more source