Population analysis of the GLB1 gene in South Brazil
Infantile GM1 gangliosidosis is caused by the absence or reduction of lysosomal beta-galactosidase activity. Studies conducted in Brazil have indicated that it is one of the most frequent lysosomal storage disorders in the southern part of the country ...
Cléia Baiotto+6 more
doaj +1 more source
Developing a far-red fluorogenic beta-galactosidase probe for senescent cell imaging and photoablation. [PDF]
Lee SK, Shen Z, Han MS, Tung CH.
europepmc +1 more source
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu+18 more
wiley +1 more source
Reversal of senescence-associated beta-galactosidase expression during in vitro three-dimensional tissue-engineering of human chondrocytes in a polymer scaffold. [PDF]
Katoh S+6 more
europepmc +1 more source
A Beta-galactosidase-producing bacterium, strain KNOUC114 isolated from a hot spring was identified, and its gene of Beta-galactosidase and properties of the enzyme were studied. The strain KNOUC114 showed typical properties of genus Thermus with phenotypic characteristics of rod-shape (0.2x3.5 um), Gram negative, non-motile, endospore not observed ...
Jong Kun Ahn+4 more
openaire +2 more sources
The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian+13 more
wiley +1 more source
Mineral Analysis, In Vitro Evaluation of Alpha-Amylase, Alpha-Glucosidase, and Beta-Galactosidase Inhibition, and Antibacterial Activities of Juglans regia L. Bark Extracts. [PDF]
Boulfia M, Lamchouri F, Toufik H.
europepmc +1 more source
DNA-directed peptide synthesis. II. The synthesis of the alpha-fragment of the enzyme beta-galactosidase. [PDF]
J K DeVries, Geoffrey Zubay
openalex +1 more source
Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou+7 more
wiley +1 more source
Valuation of agro-industrial wastes as substrates for heterologous production of α-galactosidase
Background The recycling of agro-industrial wastes is at present limited by the availability of efficient and low-cost enzyme cocktails. The use of these materials as culture media to produce the enzymes can contribute to the profitability of the ...
María-Efigenia Álvarez-Cao+4 more
doaj +1 more source