Results 91 to 100 of about 871,979 (295)

Streamlining the Detection of Human Thyroid Receptor Ligand Interactions with XL1-Blue Cell-Free Protein Synthesis and Beta-Galactosidase Fusion Protein Biosensors. [PDF]

Life (Basel), 2023
Hunt JP, Free TJ, Galiardi J, Watt KM, Wood DW, Bundy BC.   +5 more
europepmc   +1 more source

Identification of bacteria with beta-galactosidase activity in faeces from lactase non-persistent subjects

, 2005
Previous studies suggest that, besides the maldigestion of lactose in the small intestine, the colonic processing of lactose might play a role in lactose intolerance.
Tao, H, Priebe, MG, Vonk, RJ, Welling, GW   +3 more
core   +1 more source

A Dual‐Functional Nanoplatform Targeting the dsDNA–cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

Advanced Science, EarlyView.
RU@PEI‐ZIF integrates dsDNA scavenging with local cGAS inhibition to suppress the dsDNA–cGAS–STING/Netrin‐1 axis in intervertebral disc degeneration. By attenuating nucleus pulposus cell senescence, inflammatory and matrix‐catabolic responses, and pathological sensory innervation, this dual‐functional nanoplatform preserves disc integrity and reduces ...
Zhaojun He, Tianyu Chen, Zezheng Liu, Xinlin Huang, Ruitangbin Jiang, Yihao Liu, Baojing Xu, Yuxiang Li, Kangning Zhao, Huibo Yan, Lei Zhou, Can Liu, Qingchu Li   +12 more
wiley   +1 more source

Potential Effects of Selected Synthetic Cannabinoids on Neuronal Senescence: Impact on Proliferation and Beta-Galactosidase Activity in SH-SY5Y Cells

Emerging Trends in Drugs, Addictions, and Health
Introduction: Synthetic cannabinoids (SC) display a pharmacological mechanism similar to that of Δ9-tetrahydrocannabinol (THC), the key active principle of cannabis.
R. Roque-Bravo, H. Carmo, J. Pedro Silva, F. Carvalho, D. Dias da Silva   +4 more
doaj   +1 more source

Effect of exogenous beta-galactosidase in patients with lactose malabsorption and intolerance: a crossover double-blind placebo-controlled study.

, 2005
OBJECTIVE: To evaluate the efficacy of the addition to milk, 5 min and 10 h before its consumption, of a lactase obtained from Kluyveromyces lactis in lactose malabsorbers with intolerance.
Montalto, Massimo, Nucera, Gabriella, Gasbarrini, Antonio, Covino, Marcello, Gasbarrini, Giovanni Battista, Manna, Raffaele, Santoro, Luca, Vastola, Monica, Curigliano, Valentina   +8 more
core  

Disabling COMPASS Promoter Licensing Shifts HDAC‐Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery

Advanced Science, EarlyView.
Combined inhibition of the WDR5 WIN pocket and HDAC activity converts SAHA‐induced hyperacetylation into a promoter state with reduced WDR5–COMPASS association and H3K4me3. MYC/E2F‐linked nascent transcription and biosynthetic recovery are suppressed, while apoptosis and senescence‐like features increase, resulting in sustained growth inhibition in ...
Jintian Song, Hui Yu, Jianping Jiang, Zhihui Jiang, Zhongshi Hong, Xu Zhang, Luchuan Chen, Shenghong Wei, Yi Wang   +8 more
wiley   +1 more source

Development of a solid-phase enzyme immunoassay for ursodeoxycholic acid: application to plasma disappearance of injected ursodeoxycholic acid in the rabbit.

Journal of Lipid Research, 1979
A bile acid disappearance test using an enzyme immunoassay for ursodeoxycholic acid (UDCA) is presented. The immunoassay employs an antiserum produced in rabbits with UDCA coupled by amide linkage to egg albumin.
Y Maeda, T Setoguchi, T Katsuki, E Ishikawa   +3 more
doaj   +1 more source

Beta-galactosidase gene family genome-wide identification and expression analysis of members related to fruit softening in melon (Cucumis melo L.). [PDF]

BMC Genomics, 2022
Pan H, Sun Y, Qiao M, Qi H.
europepmc   +1 more source

beta-Galactosidase enzyme fragment complementation for the measurement of Wnt/beta-catenin signaling [PDF]

, 2009
Wnt/beta-catenin signaling is an important regulator of cell polarity, proliferation, and stem cell maintenance during development and adulthood.
Blankesteijn, W. Matthijs, Verkaar, Folkert, Smits, Jos F. M., Zaman, Guido J. R., Guido J. R. Zaman, W. Matthijs Blankesteijn, Folkert Verkaar, Jos F. M. Smits   +7 more
core   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source