Results 71 to 80 of about 871,979 (295)

Experimental studies on the kinetics of adsorption of beta-galactosidase interacting with immobilized anti-beta-galactosidase

, 1989
The adsorption of beta-galactosidase (BG) from solution by anti-beta-galactosidase monoclonal antibody (ABG) immobilized on nonporous, glass coated beads has been studied in a stirred batch adsorber at 4, 8, 15, and 20°C and for different initial BG ...
Hearn, Barbara June
core   +1 more source

72 residues of gal repressor fused to beta-galactosidase repress the gal operon of E. coli

, 1983
An active gene has been constructed which produces a chimera consisting of the N−terminal domain of the gal repressor and all but the first five residues of beta−galactosidase.
von Wilcken−Bergmann, B., Koenen, M., Müller−Hill, B., Griesser, H.   +3 more
core   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

X-Gal staining of tissues from ApoF KO mice harboring a beta-galactosidase reporter gene.

, 2012
The targeted ApoF allele contains a beta-galactosidase reporter gene in place of ApoF. X-gal staining was performed on a wild type (WT) and an ApoF KO mouse (KO) to examine ApoF expression.
Sumeet A. Khetarpal (182252), George H. Rothblat (182272), Denise Drazul-Schrader (182268), Sarah F. Hamm-Alvarez (182267), Daniel J. Rader (113673), Wen Lin (36325), William R. Lagor (182248), Arthi Kumaravel (182255), Kaijin Wu (182262), David W. Fields (182249), Margarita de la Llera-Moya (182270), Nathaniel Weintraub (182258)   +11 more
core   +1 more source

Bovine testicular [beta]-galactosidase: Purification of enzyme fractions that exhibit high affinity for phosphomannosyl receptors [PDF]

, 1989
An improved method is described for the preparation of bovine testicular [beta]-galactosidase that allows the isolation of enzyme fractions that bind avidly to phosphomannosyl receptors.
Distler, Jack J., Guo, Jinfeng, Jourdian, George W., Sahagian, G. Gary   +3 more
core   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study

Clinical Interventions in Aging, 2012
Salvatore Rinaldi,1,2 Margherita Maioli,1,3,4 Sara Santaniello,3,4 Alessandro Castagna,1,2 Gianfranco Pigliaru,3,4 Sara Gualini,3,4 Matteo Lotti Margotti,5 Arturo Carta,6 Vania Fontani,1,2 Carlo Ventura1,4,71Department of Regenerative Medicine, Rinaldi ...
Rinaldi S, Maioli M, Santaniello S, Castagna A, Pigliaru GF, Gualini S, Margotti ML, Carta A, Fontani V, Ventura C   +9 more
doaj  

Immobilization of mold beta-galactosidase

, 1988
We immobilized beta-galactosidase (EC 3.2.1.23) from the mold Aspergillus oryzae by various methods on the derivatives of bead cellulose manufactured by Czechoslovak industry.
Jiří Kučera, Alexandra Prošková, Milena Kmínková   +2 more
core   +1 more source

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen, Kun Mei, Yan Yang, Mengna Xu, Xinyue Dai, Renjun Gu, Fuqiong Zhou, Cheng Wang, Meiqi Chang, Yan Huang, Yu Chen   +10 more
wiley   +1 more source

Population analysis of the GLB1 gene in South Brazil

Genetics and Molecular Biology, 2011
Infantile GM1 gangliosidosis is caused by the absence or reduction of lysosomal beta-galactosidase activity. Studies conducted in Brazil have indicated that it is one of the most frequent lysosomal storage disorders in the southern part of the country ...
Cléia Baiotto, Fernanda Sperb, Ursula Matte, Cláudia Dornelles da Silva, Renata Sano, Janice Carneiro Coelho, Roberto Giugliani   +6 more
doaj   +1 more source