Results 61 to 70 of about 76,944 (297)

Study of β-Galactosidase Enzyme Activity Produced by Lactobacilli in Milk and Cheese

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
<p>Background and objective Lactose intolerance is a discomfort state that occurs in some people after ingestion of milk and it is due to insufficient amount of beta galactosidase in the human gut to digest lactose.
J Nowroozi
doaj  

A Type System for a Stochastic CLS [PDF]

open access: yes, 2009
The Stochastic Calculus of Looping Sequences is suitable to describe the evolution of microbiological systems, taking into account the speed of the described activities.
Angelo Troina   +3 more
core   +4 more sources

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

open access: yesAdvanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis [PDF]

open access: yes, 1993
To contribute to an understanding of the roles and mechanisms of action of Wnts in early vertebrate development, we have characterized the normal expression of Xenopus laevis Wnt-5A, and investigated the consequences of misexpression of this putative ...
Campbell, Robert M.   +5 more
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Screening of Spore-Forming Bacteria with Probiotic Potential in Pristine Algerian Caves

open access: yesMicrobiology Spectrum, 2022
The interest and exploration of biodiversity in subsurface ecosystems have increased significantly during the last 2 decades. The aim of this study was to investigate the in vitro probiotic properties of spore-forming bacteria isolated from deep caves ...
Baraa Rehamnia   +3 more
doaj   +1 more source

Developing a mouse model to study the metabolic role of the mammalian target of rapamycin complex 1 in adipose tissue [PDF]

open access: yes, 2016
The term "diabesity" is a pandemic that is threatening populations worldwide and is the term is finding itself as a household name, fueling itself through the high-fat diet and sedentary lifestyle.
Thimmiah, Harun
core   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

PRODUCTION OF BETA-GALACTOSIDASE IN SUBMERGED MEDIA BY ASPERGILLUS ORYZAE, PTCC 5 163 [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1997
Different compositions of liquid media were used for their efficacy in the production of beta-galactosidase by Aspergillus oryzae in submerged fermentation.
doaj  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

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