Results 41 to 50 of about 13,662 (253)

Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages

Frontiers in Immunology, 2021
Beta-glucans enable functional reprogramming of innate immune cells, a process defined as “trained immunity”, which results in enhanced host responsiveness against primary (training) and/or secondary infections (resilience).
Bart G. J. Moerings, Bart G. J. Moerings, Priscilla de Graaff, Priscilla de Graaff, Matthew Furber, Renger F. Witkamp, Reno Debets, Jurriaan J. Mes, Jeroen van Bergenhenegouwen, Coen Govers, Coen Govers   +10 more
doaj   +1 more source

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

Advanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang, Ning Lu, Xin‐Xiu Lin, Xu‐Hui Fang, Yi‐Hui Li, Qing‐Peng Luo, Yu‐Ting Peng, Gil Mor, Ai‐Hua Liao   +8 more
wiley   +1 more source

Detection of Beta-Glucan Contamination in Nanotechnology-Based Formulations

Molecules, 2020
Understanding the potential contamination of pharmaceutical products with innate immunity modulating impurities (IIMIs) is essential for establishing their safety profiles.
Barry W. Neun, Edward Cedrone, Timothy M. Potter, Rachael M. Crist, Marina A. Dobrovolskaia   +4 more
doaj   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

Advanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri, Leala Carbonneau, Eric M. Roberts, Alison W. Roberts, Candace H. Haigler, Alexey V. Gulyuk, Yaroslava G. Yingling   +6 more
wiley   +1 more source

The wound healing effect of four types of beta-glucan

Applied Biological Chemistry, 2019
Beta-glucans, which existed in the cell walls of cereals, bacteria, and fungi, comprise a group of β-d-glucose polysaccharides. We investigated the effects of four kinds of beta-glucan, that are derived from barley, yeast, mushroom, and euglena on wound ...
Gayoung Seo, Changlim Hyun, Seungin Choi, Young Mee Kim, Moonjae Cho   +4 more
doaj   +1 more source

Thermal Expansion Coefficient of Curdlan Tripropionate Measured by Thermal Mechanical Analysis and Wide‐Angle X‐Ray Diffraction

Journal of Applied Polymer Science, EarlyView.
This study demonstrates the thermal expansion behavior of curdlan tripropionate films using thermal mechanical analysis and synchrotron WAXD. Both amorphous and crystalline films show characteristic expansion near the glass transition, providing structural insights for designing heat‐resistant polysaccharide‐based plastics.
Taizo Kabe, Tadahisa Iwata
wiley   +1 more source

Visão retrospectiva em fibras alimentares com ênfase em beta-glucanas no tratamento do diabetes

Brazilian Journal of Pharmaceutical Sciences, 2009
Fibra alimentar refere-se aos componentes de plantas ou carboidratos análogos que são resistentes à digestão e absorção no intestino delgado humano. A American Dietetic Association recomenda ingestão de 20-35g de fibras ao dia. Evidências sugerem que uma
Giane Sprada Mira, Hans Graf, Lys Mary Bileski Cândido   +2 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Beta-glucan-enriched diets improve immune function, antioxidant activity, and survivability in challenged oysters

Food Hydrocolloids for Health
Beta-glucans are bioactive polysaccharides with immunomodulatory and hydrocolloid properties. This study explores the potential of beta-glucans extracted from mushroom waste to enhance oyster (Crassostrea gigas) immunity and quality, providing a ...
Gustavo Waltzer Fehrenbach, João Rui Tanoeiro, Robert Pogue, Frank Carter, Marco F.L. Lemos, Patrick Murray, Declan Devine, Emanuele Rezoagli, Ian Major, Emma J. Murphy   +9 more
doaj   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source