Results 51 to 60 of about 15,075 (247)

Detection of Beta-Glucan Contamination in Nanotechnology-Based Formulations

Molecules, 2020
Understanding the potential contamination of pharmaceutical products with innate immunity modulating impurities (IIMIs) is essential for establishing their safety profiles.
Barry W. Neun, Edward Cedrone, Timothy M. Potter, Rachael M. Crist, Marina A. Dobrovolskaia   +4 more
doaj   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

Advanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu, Jian Zhang, Jingjing Ma   +11 more
wiley   +1 more source

Oral beta-glucan adjuvant therapy converts nonprotective Th2 response to protective Th1 cell-mediated immune response in mammary tumor-bearing mice.

Folia Histochemica et Cytobiologica, 2007
Beta (1-3)-D-glucans were identified almost 40 years ago as biological response modifiers that stimulated tumor rejection. In vitro studies have shown that beta-glucans bind to a lectin domain within complement receptor type 3 (CR3), or to, more recently
Gordon D Ross, Feng Hong, Daniel J Allendorf, Jarek Baran   +3 more
doaj   +1 more source

Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody

Frontiers in Microbiology, 2020
Invasive fungal infections (IFI) cause devastating morbidity and mortality, with the number of IFIs more than tripling since 1979. Our laboratories were the first to demonstrate that radiolabeled microorganism-specific monoclonal antibodies are highly ...
Muath Helal, Kevin J. H. Allen, Bruce van Dijk, Joshua D. Nosanchuk, Elisabeth Snead, Ekaterina Dadachova   +5 more
doaj   +1 more source

Hierarchical Organization of Biomaterials in the Formation of Photonic Nanostructures

Advanced Science, EarlyView.
Natural organisms create vibrant structural colors through precisely organized nanostructures formed under mild biological conditions. This review explores how cellulose, chitin, corneous beta‐protein, and melanin form complex nanostructures across molecular, mesoscale, and tissue levels.
Sangyeop Kim, Jihun Kang, Seunghwan Moon, Liliana D'Alba, Matthew D. Shawkey, Jong‐Souk Yeo   +5 more
wiley   +1 more source

INFLUENCE OF FORTIFICATION OF DAIRY PRODUCTS BY PLEUROTUS OSTREATUS BETA-GLUCANS ON PRODUCT CHARACTERISTICS

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2019
Dairy products are often used as a base for functional food products. Preparations obtained from Pleurotus ostreatus possess antitumor, immunomodulating, anti-inflammatory, antioxidant, antibiotic, radioprotective and hypoglycemic actions.
EKATERINA ANTONTCEVA, SERGEI SOROKIN , VIKTORIYA SEDYKH, LUDMILA KRASNIKOVA, MARK SHAMTSYAN   +4 more
doaj  

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Cross‐Species Single‐Cell Comparative Analysis Reveals Gluconeogenic Features of Hepatocytes in Ruminants

Animal Research and One Health, EarlyView.
In this study, we used cross‐species comparisons to identify ruminant hepatocyte features. We also identified potential genes and TFs involved in coordinating gluconeogenesis in ruminant hepatocytes. By integrating single‐cell data with population genetic analyses, we further identified candidate genetic variation in glucose metabolism and ...
Yaqi Zhou, Wuqiang Huo, Yingran Liu, Yihang Liu, Fei Wang, Tao Shi, Yu Jiang   +6 more
wiley   +1 more source

Beta-glucan-enriched diets improve immune function, antioxidant activity, and survivability in challenged oysters

Food Hydrocolloids for Health
Beta-glucans are bioactive polysaccharides with immunomodulatory and hydrocolloid properties. This study explores the potential of beta-glucans extracted from mushroom waste to enhance oyster (Crassostrea gigas) immunity and quality, providing a ...
Gustavo Waltzer Fehrenbach, João Rui Tanoeiro, Robert Pogue, Frank Carter, Marco F.L. Lemos, Patrick Murray, Declan Devine, Emanuele Rezoagli, Ian Major, Emma J. Murphy   +9 more
doaj   +1 more source