Results 1 to 10 of about 88,294 (292)

Beta-lactam-associated hypokalemia [PDF]

open access: yesJournal of International Medical Research
The aim of this narrative review was to discuss the literature on β-lactam antibiotic-associated hypokalemia, a potentially life-threatening electrolyte disorder.
Muriel-N. Jansen   +6 more
doaj   +4 more sources

Beta-Lactam Dose Optimisation in the Intensive Care Unit: Targets, Therapeutic Drug Monitoring and Toxicity

open access: yesAntibiotics, 2023
Beta-lactams are an important family of antibiotics used to treat infections and are commonly used in critically ill patients. Optimal use of these drugs in the intensive care unit (ICU) is important because of the serious complications from sepsis ...
Amy Legg   +4 more
doaj   +3 more sources

PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance [PDF]

open access: yesMicroorganisms, 2018
β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Thaina M. da Costa   +3 more
doaj   +4 more sources

Digital five-step questionnaire to enhance standard perioperative prophylaxis in surgical patients with reported allergy to beta-lactam-antibiotics [PDF]

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Most self-reported beta-lactam antibiotic (BLA) allergies are inaccurate. This study evaluated a digital tool designed to reassess beta-lactam allergies and enable the use of standard perioperative antibiotic prophylaxis (PAP) without the ...
Daniel Röder   +5 more
doaj   +2 more sources

Promising Future of Novel Beta-Lactam Antibiotics Against Bacterial Resistance [PDF]

open access: yesDrug Design, Development and Therapy
Saeed M Tayeb,1 Jaser A Alharbi,1 Bushra B Alattas,1 Dana M Alotaibi,1 Nawaf M Althibaiti,1 Jaser F Alharbi,1 Ahmad E SafirAldeen,1 Ibrahim R Alqurashi,1 Saad M Wali2 1Pharmaceutical Sciences Department, College of Pharmacy, Umm Al-Qura University ...
Tayeb SM   +8 more
doaj   +2 more sources

Building a Beta‐Lactam Model‐Informed Precision Dosing Service in a Quaternary Care Children's Hospital [PDF]

open access: yesClinical and Translational Science
There has been growing interest in precision dosing of beta‐lactam antibiotics in recent years. At our institution, a quaternary children's hospital, we launched a new PK consult service utilizing a model‐informed precision dosing (MIPD) approach to ...
Sonya Tang Girdwood   +12 more
doaj   +2 more sources

Impact of beta-lactam allergy labels on bone marrow transplant patients [PDF]

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Approximately 95% of patients with a beta-lactam allergy noted in their medical record are not truly allergic when tested. These patients may unnecessarily avoid first-line antibiotics, resulting in increased treatment failure, higher costs ...
Benjamin M. Haxby   +5 more
doaj   +2 more sources

Delabelling beta-lactam allergy

open access: yesFrontiers in Pharmacology
Background: Hypersensitivity to beta-lactam (BL) antibiotics is one of the most frequent reported drug allergies. In our population, it is common to find labels of BL allergy in electronic medical records (EMRs) that have not been assessed. The objective
Gustavo-Jorge Molina-Molina   +21 more
doaj   +7 more sources

Daptomycin versus beta-lactam based therapy for the treatment of enterococcal endocarditis and other endovascular infections: a retrospective cohort study [PDF]

open access: yesBMC Infectious Diseases
Background Daptomycin has a favorable efficacy and safety profile against enterococcal infections, but it is currently a last line treatment for enterococcal infective endocarditis (EIE) due to limited evidence supporting its use.
Vindya Perera   +4 more
doaj   +2 more sources

Overview of Beta-Lactam Allergy and the Role of the Pharmacist in Management

open access: yesAllergies, 2021
Unverified beta-lactam allergies are a substantial public health problem, as the majority of patients labeled as beta-lactam allergic do not have clinically significant allergies that may hinder the use beta-lactam therapy when indicated.
Nicole Bradley   +2 more
doaj   +1 more source

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