Results 1 to 10 of about 63,634 (227)

Endopeptidase-mediated beta lactam tolerance. [PDF]

PLoS Pathogens, 2015
In many bacteria, inhibition of cell wall synthesis leads to cell death and lysis. The pathways and enzymes that mediate cell lysis after exposure to cell wall-acting antibiotics (e.g.
Tobias Dörr, Brigid M Davis, Matthew K Waldor   +2 more
doaj   +3 more sources

Digital five-step questionnaire to enhance standard perioperative prophylaxis in surgical patients with reported allergy to beta-lactam-antibiotics [PDF]

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Most self-reported beta-lactam antibiotic (BLA) allergies are inaccurate. This study evaluated a digital tool designed to reassess beta-lactam allergies and enable the use of standard perioperative antibiotic prophylaxis (PAP) without the ...
Daniel Röder, Kathrin Eichhorn, Johanna Stoevesandt, Jan Stumpner, Patrick Meybohm, Güzin Surat   +5 more
doaj   +2 more sources

Promising Future of Novel Beta-Lactam Antibiotics Against Bacterial Resistance [PDF]

Drug Design, Development and Therapy
Saeed M Tayeb,1 Jaser A Alharbi,1 Bushra B Alattas,1 Dana M Alotaibi,1 Nawaf M Althibaiti,1 Jaser F Alharbi,1 Ahmad E SafirAldeen,1 Ibrahim R Alqurashi,1 Saad M Wali2 1Pharmaceutical Sciences Department, College of Pharmacy, Umm Al-Qura University ...
Tayeb SM, Alharbi JA, Alattas BB, Alotaibi DM, Althibaiti NM, Alharbi JF, SafirAldeen AE, Alqurashi IR, Wali SM   +8 more
doaj   +2 more sources

Building a Beta‐Lactam Model‐Informed Precision Dosing Service in a Quaternary Care Children's Hospital [PDF]

Clinical and Translational Science
There has been growing interest in precision dosing of beta‐lactam antibiotics in recent years. At our institution, a quaternary children's hospital, we launched a new PK consult service utilizing a model‐informed precision dosing (MIPD) approach to ...
Sonya Tang Girdwood, Ronaldo Morales Junior, Erin Schuler, Peter Tang, Emily Diseroad, Catherine Misch, Beverly Engle, Shawn McCall, Mark E. Murphy, Zachary L. Taylor, Tomoyuki Mizuno, Alexander A. Vinks, Jennifer Kaplan   +12 more
doaj   +2 more sources

Beta-lactam plus macrolide treatment versus beta-lactam monotherapy for community-acquired pneumonia: a propensity score analysis using data from a multicenter prospective cohort study. [PDF]

BMC Infect Dis
Nakashima K, Aoshima M, Matusi H, Shiraishi A, Ito H, Suzuki M, Morimoto K, Ariyoshi K, Adult Pneumonia Study Group – Japan.   +8 more
europepmc   +2 more sources

Impact of beta-lactam allergy labels on bone marrow transplant patients [PDF]

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Approximately 95% of patients with a beta-lactam allergy noted in their medical record are not truly allergic when tested. These patients may unnecessarily avoid first-line antibiotics, resulting in increased treatment failure, higher costs ...
Benjamin M. Haxby, Kendall J. Tucker, Caitlin M. McCracken, YoungYoon Ham, Jon P. Furuno, Jessina C. McGregor   +5 more
doaj   +2 more sources

Impact of Timing of Beta-Lactam Therapeutic Drug Monitoring and Therapy Adjustment in Critically Ill Patients [PDF]

Antibiotics
Purpose: To assess the impact of beta-lactam therapeutic drug monitoring (TDM) timing and therapy adjustment on clinical cure and 30-day mortality. Methods: This was a prospective study of critically ill patients admitted to the University of Florida ...
Mohammad H. Alshaer, Nicole F. Maranchick, Kelly L. Maguigan, Bethany R. Shoulders, Mays J. Mousa, Melissa Murray, Jennifer Ashton, Kaitlin Alexander, Barbara A. Santevecchi, Kathryn DeSear, Veena Venugopalan, Kartikeya Cherabuddi, Charles A. Peloquin   +12 more
doaj   +2 more sources

Daptomycin versus beta-lactam based therapy for the treatment of enterococcal endocarditis and other endovascular infections: a retrospective cohort study [PDF]

BMC Infectious Diseases
Background Daptomycin has a favorable efficacy and safety profile against enterococcal infections, but it is currently a last line treatment for enterococcal infective endocarditis (EIE) due to limited evidence supporting its use.
Vindya Perera, Lynn Wardlow, Mohammad M. Sobhanie, Kelci Coe, Jessica M. Leininger   +4 more
doaj   +2 more sources

Beta-lactam-associated hypokalemia [PDF]

Journal of International Medical Research
The aim of this narrative review was to discuss the literature on β-lactam antibiotic-associated hypokalemia, a potentially life-threatening electrolyte disorder.
Muriel-N. Jansen, Wajima Safi, Igor Matyukhin, Friedrich Stasche, Johanna Tennigkeit, Oliver Ritter, Daniel Patschan   +6 more
doaj   +2 more sources

Overview of Beta-Lactam Allergy and the Role of the Pharmacist in Management

Allergies, 2021
Unverified beta-lactam allergies are a substantial public health problem, as the majority of patients labeled as beta-lactam allergic do not have clinically significant allergies that may hinder the use beta-lactam therapy when indicated.
Nicole Bradley, Yuman Lee, Dana Weinstein   +2 more
doaj   +1 more source