Results 21 to 30 of about 63,634 (227)

Clinical impact of using fluoroquinolone with low antimycobacterial activity on treatment delay in tuberculosis: Hospital-based and population-based cohort study

Journal of the Formosan Medical Association, 2020
Background/Purpose: Little remains known regarding whether newer FQ with less anti-mycobacterial activity (gemifloxacin) would reduce treatment delay. Methods: We identified one hospital-based cohort (HBC) and one population-based cohort (PBC) including ...
Meng-Rui Lee, Chih-Hsin Lee, Jann-Yuan Wang, Shih-Wei Lee, Jen-Chung Ko, Li-Na Lee   +5 more
doaj   +1 more source

Beta-lactam dosing during continuous renal replacement therapy: a survey of practices in french intensive care units

BMC Nephrology, 2022
Background Little information is available on current practice in beta-lactam dosing during continuous renal replacement therapy (CRRT). Optimized dosing is essential for improving outcomes, and there is no consensus on the appropriate dose regimens. The
Elodie Matusik, Justine Lemtiri, Guillaume Wabont, Fabien Lambiotte   +3 more
doaj   +1 more source

Management of Beta-Lactam Antibiotics Allergy: A Real-Life Study

Frontiers in Allergy, 2022
Beta-lactam allergy is a common problem in everyday medical practice and is recognized as a major public health issue. Carrying this label frequently leads to the avoidance of all beta-lactam antibiotics, favoring the use of other less preferred classes ...
Sarah Iuliano, Sarah Iuliano, Laurence Senn, Laurence Senn, Laura Moi, Laura Moi, Yannick D. Muller, Yannick D. Muller, Camillo Ribi, Camillo Ribi, Guillaume Buss, Guillaume Buss, Denis Comte, Denis Comte   +13 more
doaj   +1 more source

Allergic Reactions and Cross-Reactivity Potential with Beta-Lactamase Inhibitors

Pharmacy, 2019
Although beta-lactam allergies are an emerging focus of stewardship programs and interventions, less is publicly released regarding allergies to beta-lactamase inhibitors. This review presents and evaluates the data regarding allergic reactions with beta-
Kayla R. Stover, Katie E. Barber, Jamie L. Wagner   +2 more
doaj   +1 more source

Historical Review of the Penicillin and Related Compounds (β – Lactams)

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
In spite of  the old age of beta lactam, they continue to provide good health and preventing human diseases by virtue of  industrial production and discoveries of small new beta-lactam group of secondary metabolite.
Luma Salman Abd
doaj   +1 more source

Beta-lactam antibiotic test doses in the emergency department

World Allergy Organization Journal, 2020
Background: Facilitating beta-lactam antibiotic use in patients reporting beta-lactam allergies in acute care settings is important to individual patient outcomes and public health; however, few initiatives have targeted the Emergency Department (ED ...
Michelle Maguire, Bryan D. Hayes, Lanting Fuh, Ramy Elshaboury, Ronak G. Gandhi, Sarah Bor, Erica S. Shenoy, Anna R. Wolfson, Christian M. Mancini, Kimberly G. Blumenthal   +9 more
doaj   +1 more source

Setting the Beta-Lactam Therapeutic Range for Critically Ill Patients: Is There a Floor or Even a Ceiling?

Critical Care Explorations, 2021
OBJECTIVES:. Beta-lactam antibiotics exhibit high interindividual variability in drug concentrations in patients with critical illness which led to an interest in the use of therapeutic drug monitoring to improve effectiveness and safety.
Erin F. Barreto, PharmD, MSc, Andrew J. Webb, PharmD, Gwendolyn M. Pais, PhD, Andrew D. Rule, MD, Paul J. Jannetto, PhD, Marc H. Scheetz, PharmD, MSc   +5 more
doaj   +1 more source

Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods study

Implementation Science Communications, 2021
Background Beta-lactams (i.e., penicillins, cephalosporins, carbapenems, monobactams) are the most widely used class of antibiotics in critically ill patients.
Erin F. Barreto, Andrew D. Rule, Mohammad H. Alshaer, Jason A. Roberts, Mohd Hafiz Abdul Aziz, Marc H. Scheetz, Kristin C. Mara, Paul J. Jannetto, Ognjen Gajic, John C. O’Horo, Kasey R. Boehmer   +10 more
doaj   +1 more source

Molecular characterization of ESBL-producing Shigella sonnei isolates from patients with bacilliary dysentery in Lebanon

Journal of Infection in Developing Countries, 2009
Background: Emergence of extended-spectrum -lactamases (ESBLs) in Shigella species imparting resistance to third-generation cephalosporins is a growing concern worldwide. The aim of this study is to molecularly characterize the newly emerging beta-lactam
Ahmad H. Sabra, George F. Araj, Mireille M. Kattar, Roland Y. Abi-Rached, Marie-Therese Khairallah, John D. Glena, Ghassan M. Matar   +6 more
doaj   +1 more source

Role of a Real-Time TDM-Based Expert Clinical Pharmacological Advice Program in Optimizing the Early Pharmacokinetic/Pharmacodynamic Target Attainment of Continuous Infusion Beta-Lactams among Orthotopic Liver Transplant Recipients with Documented or Suspected Gram-Negative Infections

Antibiotics, 2023
(1) Objectives: To describe the attainment of optimal pharmacokinetic/pharmacodynamic (PK/PD) targets in orthotopic liver transplant (OLT) recipients treated with continuous infusion (CI) beta-lactams optimized using a real-time therapeutic drug ...
Milo Gatti, Matteo Rinaldi, Cristiana Laici, Antonio Siniscalchi, Pierluigi Viale, Federico Pea   +5 more
doaj   +1 more source