Results 141 to 150 of about 52,329 (268)

Extended-spectrum beta-lactamases [PDF]

Antimicrobial Agents and Chemotherapy, 1989
A Philippon, Roger Labia, George A. Jacoby   +2 more
openaire   +3 more sources

APH Inhibitors that Reverse Aminoglycoside Resistance in Enterococcus casseliflavus

ChemMedChem, Volume 20, Issue 8, April 14, 2025.
Molecular dynamics simulations and in silico screening were used to identify non‐competitive inhibitors of APH, the enzymes that confer resistance to aminoglycoside antibiotics. A hit molecule showed activity against APH(2′′)‐IVa. Allosteric inhibition by the hit molecule and a two‐fold more potent analogue was confirmed by enzymatic measurements. Both
Elise Kaplan, Laurent Chaloin, Jean‐François Guichou, Kévin Berrou, Rahila Rahimova, Gilles Labesse, Corinne Lionne   +6 more
wiley   +1 more source

Disc agar diffusion antimicrobial susceptibility tests with .BETA.-lactamase producing Neisseria gonorrhoeae.

, 1978
J W Biddle, Jana M. Swenson, Clyde Thornsberry   +2 more
openalex   +2 more sources

Characterization of beta-lactamases

Antimicrobial Agents and Chemotherapy, 1989
openaire   +4 more sources

Increased-Resistance Phenotype Resulted from Elevated β-Lactamase Enzyme Activity in Salmonella Clinical Isolates

مجله دانشکده پزشکی اصفهان, 2012
Background: Beta lactamase enzymes are the most important agents involved in promoting antimicrobial resistance patterns in bacteria. The aim of the present study was to investigate probable roles of enzyme activity divergence in production of different ...
Mercedeh Tajbakhsh, Mohammad Yaghoobi Avini, Jahan Ali Khajeh, Masoud Alebouyeh, Ehsan Nazemalhosseini Mojarad, Mohammad Reza Zali   +5 more
doaj  

Measuring the capacity of yeast for surface display of cell wall‐anchored protein isoforms by using β‐lactamase as a reporter enzyme

FEBS Open Bio, Volume 15, Issue 4, Page 573-579, April 2025.
Yeast surface display (YSD) uses genetically modified yeast to immobilize recombinant enzymes on the cell surface. To quantify the efficiency of YSD, β‐lactamase was fused to selected cell wall proteins and enzyme activity was measured spectrophotometrically at 482 nm using nitrocefin as substrate. This system enables the monitoring of enzyme activity,
Tea Martinić Cezar, Antonia Paić, Stefani Prekpalaj, Renata Teparić, Bojan Žunar, Igor Stuparević   +5 more
wiley   +1 more source

<i>Streptomyces</i> sp. VITGV156 secondary metabolite binds pathogenic protein PBP2a and Beta-lactamase. [PDF]

Front Bioinform
Pattapulavar V, Ramanujam S, Shah M, Thirunavukkarasu MK, Arumugam S, Karuppasamy R, Samrot AV, Deepasree K, Venugopal S, Christopher JG.   +9 more
europepmc   +1 more source

Possible .BETA.-lactamase activities detectable in infective clinical specimens.

, 1977
Gohta MASUDA, Susumu Tomioka
openalex   +2 more sources

Genetics of resistance in a non-beta-lactamase-producing gonococcus with relatively high-level penicillin resistance [PDF]

, 1986
Hawazin Faruki, P. Frederick Sparling
openalex   +1 more source

Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy

Advanced Therapeutics, Volume 8, Issue 4, April 2025.
Tuberculosis (TB) remains a global health challenge, with drug‐resistant strains exacerbating the issue. Metallic nanoparticles (MNPs) show promise in TB diagnosis as sensor probes and in combination therapy with antimycobacterial drugs, requiring further pre‐clinical and clinical research for clinical translation.
Christianah Aarinola Akinnawo, Admire Dube   +1 more
wiley   +1 more source