Results 191 to 200 of about 52,329 (268)

Beta-lactamase/ESBL [PDF]

open access: yesClinical Microbiology and Infection, 1999
openaire   +1 more source

α/β Hydrolases: Toward Unraveling Entangled Classification

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 4, Page 855-870, April 2025.
ABSTRACT α/β Hydrolase‐like enzymes form a large and functionally diverse superfamily of proteins. Despite retaining a conserved structural core consisting of an eight‐stranded, central β‐sheet flanked with six α‐helices, they display a modular architecture allowing them to perform a variety of functions, like esterases, lipases, peptidases, epoxidases,
Fatih Ozhelvaci, Kamil Steczkiewicz
wiley   +1 more source

Metabolic Insights Into Microbially Induced Calcite Formation by Bacillaceae for Application in Bio‐Based Construction Materials

open access: yesEnvironmental Microbiology, Volume 27, Issue 4, April 2025.
Mineral formation by bacteria is a widespread, yet poorly understood, phenomenon, which finds many applications in the field of sustainable construction materials. Here, we provide insights into the physiological processes leading to non‐ureolytic biomineralisation, with acetate metabolism identified as a key driver in some environmental Bacillales ...
Michael Seidel   +9 more
wiley   +1 more source

Prevalence and antimicrobial resistance of extended spectrum beta-lactamase (ESBL) producing Klebsiella spp. in poultry meat. [PDF]

open access: yesHeliyon
Tanni FY   +8 more
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 7, Page 1416-1445, April 2025.
Abstract In the past year, the European Medicines Agency (EMA), the Food and Drug Administration (FDA) and the Medicines and Healthcare Products Regulatory Agency (MHRA) authorised 53 novel drugs. While the 2024 harvest is not as rich as in 2023, when 70 new chemical entities were approved, the number of ‘orphan’ drug authorisations in 2024 (21) is ...
Stavros Topouzis   +16 more
wiley   +1 more source

Epidemiology, Treatment, and Outcomes of Gram‐Negative Bacteremia in a Multicenter Cohort of Solid Organ Transplant Recipients

open access: yesClinical Transplantation, Volume 39, Issue 4, April 2025.
ABSTRACT Introduction Little is known about the epidemiology and management of gram‐negative bloodstream infections (GN‐BSIs) in patients after solid organ transplant (SOT). We describe epidemiology, treatment approaches, and outcomes in a subset of patients with SOT from a larger cohort with GN‐BSI. Methods This was a multicenter, retrospective cohort
Sarah B. Doernberg   +11 more
wiley   +1 more source

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