Results 131 to 140 of about 34,488 (237)

RCSB protein data Bank: Next‐generation advanced search for exploration of experimental structures and computed structure models

Protein Science, Volume 35, Issue 8, August 2026.
Abstract The Protein Data Bank (PDB), established in 1971, is the primary global, open‐access archive for experimentally determined 3D macromolecular structures (proteins, RNA, DNA). The research‐focused RCSB.org web‐portal provides access to these data alongside more than one million machine‐learning‐predicted structure models, greatly expanding the ...
Yana Rose, Ronald Brown, Maria Voigt, Charmi Bhikadiya, Sebastian Bittrich, Jose M. Duarte, Joan Segura, Rachel Kramer Green, Stephen K. Burley   +8 more
wiley   +1 more source

New Delhi metallo-β-lactamase-1: structure, inhibitors and detection of producers [PDF]

, 2016
Since its discovery in 2008, New Delhi metallo-beta-lactamase-1 (NDM-1)-producing Enterobacteriaceae have disseminated globally, facilitated predominantly by gut colonization and the spread of plasmids carrying the bla(NDM-1) gene.
David Hibbs (2925300), Paul Groundwater (536845), Linda Varadi (20019243), John Perry (3608414), Sophia Xu (12839021), Jinlong Tan (1302954), Felcia Lai (11153268)   +6 more
core  

In Vitro Activity of Cefaclor/Beta-Lactamases Inhibitors (Clavulanic Acid and Sulbactam) Combination Against Extended-Spectrum Beta-Lactamase Producing Uropathogenic E. coli

Antibiotics
Background: Urinary tract infections (UTIs) caused by the multidrug resistance (MDR) phenotype termed extended-spectrum beta lactamase (ESBL)-producing E. coli is a significant and growing global health concern.
Ali Atoom, Bayan Alzubi, Dana Barakat, Rana Abu-Gheyab, Dalia Ismail-Agha, Awatef Al-Kaabneh, Nawfal Numan   +6 more
doaj   +1 more source

Occurrence and Distribution of Environmental Pseudomonas aeruginosa From Hospitals in Bangladesh Reveals Diverse Strain Families, Multidrug Resistance, and Biofilm Formation

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Environmental reservoirs in Bangladeshi hospitals harbor phylogenetically diverse, multidrug‐resistant Pseudomonas aeruginosa with extensive biofilm‐forming capacity and class 1 integron‐associated resistance genes. These findings highlight hospital environments as persistent sources of antimicrobial resistance dissemination and underscore the need for
S. M. Kador, Tanay Chakrovarty, Khandaker Adil, Md. Mustak Ahmed, Md. Mohsin Kobir, Md. Hasanuzzaman, Mousufa Akter, Tanzima Sharmim Taowhid, Md. Tanvir Islam, Ovinu Kibria Islam   +9 more
wiley   +1 more source

Multi-Drug Resistant Gram-Negative Sepsis in Neonates: The Special Role of Ceftazidime/Avibactam and Ceftolozane/Tazobactam

Medicines
Neonatal sepsis is a major cause of morbidity and mortality in neonates. A particular concern is the increasing prevalence of antibiotic-resistant strains among neonatal intensive care units (NICUs).
Niki Dermitzaki, Foteini Balomenou, Anastasios Serbis, Natalia Atzemoglou, Lida Giaprou, Maria Baltogianni, Vasileios Giapros   +6 more
doaj   +1 more source

Inhibitor-resistant beta-lactamases [PDF]

Journal of Antimicrobial Chemotherapy, 1997
openaire   +2 more sources

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

Veterinary Record, Volume 199, Issue 2, Page e73-e81, 18/25 July 2026.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins, Peers Davies, Peter‐John Noble, Anna Bunford‐Davies, April Lawson, Gina Pinchbeck, Ifan Lloyd, Robert Smith, Alan D. Radford   +8 more
wiley   +1 more source

Acetamidomethaneboronic acids bearing the R1 side chains of beta-lactams as inhibitors of beta-lactamase enzymes [PDF]

The invention provides a method of treating a .beta.-lactam-antibiotic-resistant bacterial infection with a combination of a .beta.-lactamanalog (acylaminomethaneboronic acid deriv.). The invention also provides a method of inhibiting a .beta.-lactamase
L. C. BLASZCZAK, CASELLI, Emilia, B. K. SHOICHET, PRATI, Fabio   +3 more
core  

Fecal carriage and phylo-diversity of community-acquired blaTEM Enteric bacilli in Southwest Nigeria

Infection and Drug Resistance, 2018
Paul Akinniyi Akinduti,1 Grace Iyabo Olasehinde,1 Oluwaseun Ejilude,2 Olugbenga Samson Taiwo,1 Yemisi Dorcas Obafemi1 1Microbiology Unit, Department of Biological Sciences, Covenant University, Otta, Nigeria; 2Microbiology Unit, Sacred Heart Hospital ...
Akinduti PA, Olasehinde GI, Ejilude O, Taiwo OS, Obafemi YD   +4 more
doaj  

Punica granatum leaf extract as a natural antibacterial agent explored by experimental and computational methods

Scientific Reports
The rise of multidrug-resistant (MDR) microorganisms, particularly Escherichia coli, poses a significant threat to global public health, necessitating the development of alternative treatments.
Faria Tasnim, Md. Eram Hosen, Al Riyad Hasan, Md. Taohid Hasan, Md. Mizanur Rahaman, Md. Motaher Hossain, Md. Abdulla Al Jubayed, Md. Aktaruzzaman, Mansour Altayyar, Endalamaw Yihune, Md. Tarikul Islam, Magdi E. A. Zaki   +11 more
doaj   +1 more source