Results 181 to 190 of about 39,817 (237)

Antimicrobial susceptibility of enterobacterales causing bloodstream infection in United States medical centres: comparison of aztreonam-avibactam with beta-lactams active against carbapenem-resistant enterobacterales. [PDF]

BMC Infect Dis
Sader HS, Kimbrough JH, Mendes RE, Castanheira M.   +3 more
europepmc   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, Volume 3, Issue 1, March 2026.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

A whole-cell hypersensitive biosensor for beta-lactams based on the AmpR-AmpC regulatory circuit from the Antarctic Pseudomonas sp. IB20. [PDF]

Microb Biotechnol
Higuera-Llantén S, Alcalde-Rico M, Vasquez-Ponce F, Ibacache-Quiroga C, Blazquez J, Olivares-Pacheco J.   +5 more
europepmc   +1 more source

Resistome flow in global landfill systems

iMetaOmics, Volume 3, Issue 1, March 2026.
Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong, Rui Zhang, Xiaoxing Lin, Yangqing Wang, Shu Yang, Farees ud din Mufti, Yuping Yao, Guowei Zhou, Chuanwu Xi, Weixi Shu, Gordon Price, Youcai Zhao, Liyan Song   +12 more
wiley   +1 more source

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure

Journal of Biophotonics, Volume 19, Issue 3, March 2026.
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa, Maria Vitória S. Pereira, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis. [PDF]

Crit Care
Gatti M, Cojutti PG, Pea F.
europepmc   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source