Results 121 to 130 of about 14,075,605 (174)

True cyst formation underlies persistence and drug tolerance in Tritrichomonas foetus. [PDF]

open access: yesNat Commun
Iriarte LS   +8 more
europepmc   +1 more source

Stereochemistry and kinetics of the hydration of 2-acetamido-D-glucal by .beta.-N-acetylhexosaminidases

Biochemistry, 1994
Hydrolysis by three beta-N-acetylhexosaminidases (human placenta, jack bean, and bovine kidney) is shown to occur with the retention of anomeric configuration, most likely via a double-displacement mechanism involving the formation and hydrolysis of a glycosyl-enzyme intermediate.
Stephen Withers
exaly   +3 more sources

Beta-N-Acetylhexosaminidases accept 4-deoxy-N-acetylhexosaminides as substrates

open access: yes, 2009
b-N-Acetylhexosaminidases (EC 3.2.1.52, CAZy GH20) possess so called wobbling specificity, which means that they cleave substrates both in gluco- and galacto- configurations, with the activity ratio depending on the enzyme source. Here we present a new finding that fungal b-N-acetylhexosaminidases are also able to hydrolyze and transfer 4-deoxy-N ...
Slamova K   +6 more
openaire   +3 more sources

Inflammatory Bowel Disease and Serum Beta-N-Acetylhexosaminidase

Enzyme, 2017
Serum β-N-acetylhexosaminidase levels in 49 patients with inflammatory bowel disease (IBD; 23 patients with ulcerative colitis, 10 with Crohn’s disease, and 16 with ileostomy after total proctocolectomy) as well as in healthy normal controls were determined. They were found to be significantly elevated in 91 % of all patients, disregarding the state of
E, Scapa, M, Neuman, J, Eshchar
openaire   +2 more sources

The multiple forms and kinetic differences of rat colonic beta-N-acetylhexosaminidases.

Biochimica et biophysica acta, 1978
Rat colonic beta-N-acetylhexosaminidase (2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxyglucohydrolase, EC 3.2.1.30) has been separated into three forms by DEAE-cellulose chromatography with an increasing salt gradient. It was not possible to separate the glucosaminidase activity from the galactosaminidase activity by a variety of chromatographic ...
N, Mian, D G, Herries, E A, Batte
openaire   +2 more sources

The inhibition of β-N-acetylhexosaminidase by lactones

Biochimica et Biophysica Acta (BBA) - Enzymology, 1973
β-N-Acetylhexosaminidase (2-acetamido-2-deoxy-β-hexoside acetamidodeoxy-hexohydrolase, EC 3.2.1.52), from commercial bovine serum albumin, was inhibited by glucoheptonolactone, d- and l-gluconolactone, d-galactonolactone, d-fuconolactone, l-arabonolactone, d-ribonolactone, l-mannolactone and l-ascorbic acid. The kinetics of inhibition of the hydrolysis
J N, Kanfer, C H, Spielvogel
openaire   +2 more sources

Elevated β-N-acetylhexosaminidase activity in focal dystonia fibroblasts

Clinica Chimica Acta, 1999
Specific activities of beta-D-hexosaminidase, alpha-D-mannosidase, beta-D-galactosidase and beta-D-glucuronidase were determined in fibroblasts of patients with writer's cramp and torticollis. These diseases show degenerative neurological disorders similar to those observed in lysosomal diseases.
Costanzi Egidia   +4 more
openaire   +6 more sources

Identification of an intermediate form of β-N-acetylhexosaminidase in chorionic villi

Clinica Chimica Acta, 1990
A minor form of beta-N-acetylhexosaminidase has been found in chorionic villi, in addition to the major forms A and B. This form does not hydrolyze the 4-methylumbelliferyl-2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulpha te substrate, is thermostable, has a higher mol mass (120,000) than A and B (100,000) and on analytical isoelectric focusing, it ...
Pieretti M.   +4 more
openaire   +3 more sources

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