Results 11 to 20 of about 937 (178)

Characterization of Hyaluronidase 4 Involved in the Catabolism of Chondroitin Sulfate. [PDF]

Molecules, 2022
Hyaluronidases (HYALs) are endo-beta-N-acetylhexosaminidases that depolymerize not only hyaluronan but also chondroitin sulfate (CS) at the initial step of their catabolism. Although HYAL1 hydrolyzes both CS and HA, HYAL4 is a CS-specific endoglycosidase.
Yamada S, Mizumoto S.
europepmc   +2 more sources

Phylogenetic analyses suggest multiple changes of substrate specificity within the Glycosyl hydrolase 20 family

BMC Evolutionary Biology, 2008
Background Beta-N-acetylhexosaminidases belonging to the glycosyl hydrolase 20 (GH20) family are involved in the removal of terminal β-glycosidacally linked N-acetylhexosamine residues.
Horner David S, Pavesi Giulio, Intra Jari   +2 more
doaj   +1 more source

Immunoglobulin E‐specific allergens against leaf in serum of dogs with clinical features of grass leaf allergy

Veterinary Dermatology, Volume 34, Issue 5, Page 393-403, October 2023., 2023
Background – Grass leaf has been suspected to cause immunoglobulin (Ig)E‐mediated immediate hypersensitivity reactions both in humans and in dogs. However, most studies in this area are case control studies without in vitro data showing the involvement of IgE in the reaction.
Ken Mason, Janet Davies, Merja Ruutu
wiley   +1 more source

New approaches to Tay-Sachs disease therapy [PDF]

, 2018
Copyright © 2018 Solovyeva, Shaimardanova, Chulpanova, Kitaeva, Chakrabarti and Rizvanov. Tay-Sachs disease belongs to the group of autosomal-recessive lysosomal storage metabolic disorders.
Chakrabarti L., Chulpanova D., Kitaeva K., Rizvanov A., Shaimardanova A., Solovyeva V.   +5 more
core   +5 more sources

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

Mass Spectrometry Reviews, Volume 42, Issue 5, Page 1984-2206, September/October 2023., 2023
Abstract This review is the tenth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2020.
David J. Harvey
wiley   +1 more source

Purification and Characterization of .BETA.-N-Acetylhexosaminidase from Trichoderma harzianum.

Agricultural and Biological Chemistry, 1991
beta-N-Acetylhexosaminidase was produced by Trichoderma harzianum cultivated with chitin as the growth substrate. The enzyme was purified 13.2-fold to homogeneity by ultrafiltration and sequential chromatography on SP-Toyopearl and Sephacryl S-200. The molecular weight of the enzyme was estimated to be about 150,000 by gel filtration.
K, Koga, Y, Iwamoto, H, Sakamoto, K, Hatano, M, Sano, I, Kato   +5 more
openaire   +3 more sources

Identification of Novel Potential β-N-Acetyl-D-Hexosaminidase Inhibitors by Virtual Screening, Molecular Dynamics Simulation and MM-PBSA Calculations [PDF]

, 2012
Chitinolytic β-N-acetyl-d-hexosaminidases, as a class of chitin hydrolysis enzyme in insects, are a potential species-specific target for developing environmentally-friendly pesticides.
Arai, Arai, Case, Cohen, Essmann, Fukamizo, Gasteiger, Gouda, Guohui Li, Honig, Irwin, Irwin, Jeuniaux, Jianling Liu, Jinan Wang, Keyhani, Koga, Kollman, Kramer, Kuhn, Lee, Liu, Liu, Liu, Medina-Franco, Mengmeng Liu, Morris, Pranav Kumar, Ryckaert, Strasser, Wang, Wang, Watanabe, Weber, Welch, Xu, Yan Li, Yang, Yao Yao, Yi, Yonghua Wang   +40 more
core   +4 more sources

Purification and characterization of .BETA.-N-acetylhexosaminidase from Penicillium oxalicum.

Agricultural and Biological Chemistry, 1985
β-N-Acetylhexosaminidase (EC 3.2.1.52) was purified from the culture filtrate of Penicillium oxalicum by fractionation with ammonium sulfate followed by successive column chromatographies with DEAE-cellulose, hydroxylapatite, Sephadex G-150 and Con A-Sepharose 4B. The purified enzyme was found to be homogeneous on polyacrylamide gel electrophoresis and
Kenji YAMAMOTO, Kwang Moo LEE, Hidehiko KUMAGAI, Tatsurokuro TOCHIKURA   +3 more
openaire   +2 more sources

Purification and characterization of .BETA.-N-acetylhexosaminidase from Pycnoporus cinnabarinus.

Agricultural and Biological Chemistry, 1981
β-N-Acetylhexosaminidase (EC 3.2.1.52) was purified from the culture filtrate of Pycnoporus cinnabarinus to homogeneity by polyacrylamide disc gel electrophoresis. The ratio of β-GlcNAcase activity to β-GalNAcase activity remained constant during the purification process.
Akira OHTAKARA, Miho YOSHIDA, Motoharu MURAKAMI, Takako IZUMI   +3 more
openaire   +2 more sources

Development of unsupervised learning methods with applications to life sciences data [PDF]

, 2023
Machine Learning makes computers capable of performing tasks typically requiring human intelligence. A domain where it is having a considerable impact is the life sciences, allowing to devise new biological analysis protocols, develop patients ...
Gardini, Erika <1994>
core   +1 more source