Results 61 to 70 of about 1,317,896 (291)

Estimating discrete curvatures in terms of beta numbers

, 2016
For an arbitrary Radon measure $ $ we estimate the integrated discrete curvature of $ $ in terms of its centred variant of Jones' beta numbers. We farther relate integrals of centred and non-centred beta numbers. As a corollary, employing the recent result of Tolsa [Calc. Var.
openaire   +3 more sources

Corporate financial policies and performance around currency crises [PDF]

, 2001
Using data from 17 countries that have suffered a currency crisis, this paper studies firm-level leverage and performance measures before and after a crisis has occurred.
Adler Michael, Allayannis George, Arturo Bris, Arturo Bris, Bailey Warren, Bartov Eli, Bernard Dumas, Campbell R Harvey, Claessens Stijn, Dumas Bernard, Giancarlo Corsetti, Gordon M Bodnar, Gordon M Bodnar, James E Hodder, Kathryn Dominguez, Levich, Simon Johnson, Vicente Pascual Pons-Sanz, Yakov Amihud, Yrjo Koskinen   +19 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Comparison Effect of Prescription Drugs on the Occurrence and the Number of Attacks in Patients with Multiple Sclerosis

مجله دانشکده پزشکی اصفهان, 2018
Background: Treatment has a major effect on attacks in patients with multiple sclerosis (MS). This study aimed to determine the effect of the type of used drug on occurrence and number of attacks in patients with multiple sclerosis.
Marjan Jamalian, Vahid Shaygannejad, Soleiman Kheiri, Morteza Sedehi, Omid Mirmosayyeb   +4 more
doaj   +1 more source

Investigating the role of islet cytoarchitecture in its oscillation using a new beta-cell cluster model. [PDF]

PLoS ONE, 2007
The oscillatory insulin release is fundamental to normal glycemic control. The basis of the oscillation is the intercellular coupling and bursting synchronization of beta cells in each islet.
Aparna Nittala, Soumitra Ghosh, Xujing Wang   +2 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Density Fluctuation–Mach Number Scaling in Compressible, High Plasma Beta Turbulence: In Situ Space Observations and High-Reynolds Number Simulations

The Astrophysical Journal Letters
Understanding the nature of compressible fluctuations in a broad range of turbulent plasmas, from the intracluster medium to the solar wind, has been an active field of research in the past decades.
Riddhi Bandyopadhyay, James R. Beattie, Amitava Bhattacharjee   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Synthesis of RNA Nucleotides under Probably Prebiotic Conditions [PDF]

, 2022
RNA being composed of multiple covalently linked nucleotides is thought to have been a precursor to life circa 4.3-3.8 billion years ago. Non-enzymatically formed adenosine monophosphate (AMP), more specifically, is a vitally important subtopic of the ...
Stimson, Ryan
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source