Paradoxical association between the 316 Trp to Ser beta 2‐glycoprotein I (Beta2GPI) polymorphism and anti‐Beta2GPI antibodies [PDF]
Michael J. Nash +5 more
openalex +1 more source
The role of beta 2 glycoprotein I in inflammation and autoimmunity
Systemic lupus erythematosus is a multifactorial autoimmune disease which has been associated with several genetic, hormonal and environmental factors. TLRs are a group of innate immune system receptors and have been linked strongly to SLE development.
openaire +2 more sources
Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor +12 more
wiley +1 more source
Functional and binding studies of the roles of prothrombin and beta 2- glycoprotein I in the expression of lupus anticoagulant activity [PDF]
Parichart Permpikul, LV Rao, SI Rapaport
openalex +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Serum Proteomic Changes in Pet Rabbits with Subclinical and Clinical Encephalitozoonosis in Thailand
Encephalitozoon cuniculi causes both clinical and subclinical infections in rabbits, complicating a diagnosis due to the limitations of conventional tools like ELISA.
Taksaon Duangurai +5 more
doaj +1 more source
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Revisiting beta 2 glycoprotein I, the major autoantigen in the antiphospholipid syndrome.
Beta 2 glycoprotein I (β2GPI) is a single chain 50 kDa highly glycosylated glycoprotein at an approximate concentration of 4 μM in cells. The abundance of this protein in plasma and its high state of preservation indicate the important role of this protein in mammalians.
openaire +2 more sources
An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon +5 more
wiley +1 more source
Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials
This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker +5 more
wiley +1 more source

